NP_056362.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
67,152 Da
NCBI Official Full Name
acyl-coenzyme A thioesterase 11 isoform 1
NCBI Official Synonym Full Names
acyl-CoA thioesterase 11
NCBI Protein Information
acyl-coenzyme A thioesterase 11
UniProt Protein Name
Acyl-coenzyme A thioesterase 11
UniProt Synonym Protein Names
Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; BFIT
UniProt Synonym Gene Names
UniProt Entry Name
ACO11_HUMAN
NCBI Summary for ACOT11
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
UniProt Comments for ACOT11
ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.2.-; Hydrolase
Chromosomal Location of Human Ortholog: 1p32.3
Cellular Component: cytoplasm; cytosol
Molecular Function: acyl-CoA hydrolase activity
Biological Process: acyl-CoA metabolic process; fatty acid metabolic process; response to cold; response to temperature stimulus
Research Articles on ACOT11
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Pathways associated with anti-ACOT11 antibody
Diseases associated with anti-ACOT11 antibody
Organs/Tissues associated with anti-ACOT11 antibody
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