AAH01517.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ACOT11 protein
NCBI Official Synonym Full Names
acyl-CoA thioesterase 11
NCBI Protein Information
acyl-coenzyme A thioesterase 11; START domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase, adipose associated; thioesterase superfamily member 1; StAR-related lipid transfer (START) domain containing 14
UniProt Protein Name
Acyl-coenzyme A thioesterase 11
UniProt Synonym Protein Names
Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase
UniProt Synonym Gene Names
UniProt Entry Name
ACO11_HUMAN
NCBI Summary for ACOT11
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
UniProt Comments for ACOT11
ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.2.-; Hydrolase
Chromosomal Location of Human Ortholog: 1p32.3
Cellular Component: cytoplasm
Molecular Function: acyl-CoA hydrolase activity; lipid binding
Biological Process: response to temperature stimulus; response to cold; fatty acid metabolic process
Research Articles on ACOT11
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Diseases associated with anti-ACOT11 antibody
Organs/Tissues associated with anti-ACOT11 antibody
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