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anti-ACOT2 antibody :: Rabbit ACOT2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2525347
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACOT2, Polyclonal Antibody

★Popular Item★
 Also Known As   

ACOT2 Polyclonal Antibody

 Product Synonym Names    MTE1; PTE2; CTE1A; PTE2A; CTE-IA; ZAP128
 Product Gene Name   

anti-ACOT2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609972
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    0.6mg/mL (lot specific)
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 Immunogen    Recombinant protein of human ACOT2
 Calculated Molecular Weight: 53kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ACOT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ACOT2 antibody

   This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. Acyl-CoA thioesterases, such as ACOT2, are a group of enzymes that hydrolyze Coenzyme A (CoA) esters, such as acyl-CoAs, bile CoAs, and CoA esters of prostaglandins, to the corresponding free acid and CoA. ACOT2 shows high acyl-CoA thioesterase activity on medium- and long-chain acyl-CoAs, with an optimal pH of 8. 5. It is most active on myristoyl-CoA but also shows high activity on palmitoyl-CoA, stearoyl-CoA, and arachidoyl-CoA.
 Applications Tested/Suitable for anti-ACOT2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ACOT2 antibody    WB: 1:100-1:500
IHC: 1:15-1:50
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 Western Blot (WB) of anti-ACOT2 antibody    Western Blot analysis of MCF7 cell using ACOT2 Polyclonal Antibody at dilution of 1:150
anti-ACOT2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ACOT2 antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer using ACOT2 Polyclonal Antibody at dilution of 1:15
anti-ACOT2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ACOT2 antibody    Immunohistochemistry of paraffin-embedded Human lung cancer using ACOT2 Polyclonal Antibody at dilution of 1:15
anti-ACOT2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ACOT2. It may not necessarily be applicable to this product.
 NCBI GI #    148727286
 NCBI GeneID    10965
 NCBI Accession #    NP_006812.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_006821.5 [Other Products]
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 UniProt Secondary Accession #    Q3I5F8; Q53EK4; Q9NUX4 [Other Products]
 UniProt Related Accession #    P49753 [Other Products]
 Molecular Weight    32,959 Da
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 NCBI Official Full Name    acyl-coenzyme A thioesterase 2, mitochondrial
 NCBI Official Synonym Full Names    acyl-CoA thioesterase 2
 NCBI Official Symbol    ACOT2 [Similar Products]
 NCBI Official Synonym Symbols   
MTE1; PTE2; CTE1A; PTE2A; CTE-IA; ZAP128
[Similar Products]
 NCBI Protein Information    acyl-coenzyme A thioesterase 2, mitochondrial; acyl-coenzyme A thioester hydrolase 2a; long-chain acyl-CoA thioesterase 2; mitochondrial acyl-CoA thioesterase 1; peroxisomal long-chain acyl-coA thioesterase 2
 UniProt Protein Name    Acyl-coenzyme A thioesterase 2, mitochondrial
 UniProt Synonym Protein Names   
Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128
 Protein Family    Acyl-coenzyme A thioesterase
 UniProt Gene Name    ACOT2 [Similar Products]
 UniProt Synonym Gene Names    PTE2; PTE2A; Acyl-CoA thioesterase 2 [Similar Products]
 UniProt Entry Name    ACOT2_HUMAN
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 NCBI Summary for ACOT2    This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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 UniProt Comments for ACOT2    ACOT2: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs. Belongs to the C/M/P thioester hydrolase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.2.2; Hydrolase; Mitochondrial; Lipid Metabolism - unsaturated fatty acid biosynthesis

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrion

Molecular Function: acyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activity; receptor binding

Biological Process: acyl-CoA metabolic process; very-long-chain fatty acid metabolic process; long-chain fatty acid metabolic process
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 Research Articles on ACOT2    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ACOT2 antibodyDiseases associated with anti-ACOT2 antibody
 Products by Pathway  Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Oleate Biosynthesis Pathway antibodies  Oleate Biosynthesis Pathway Diagram
 Oleate Biosynthesis II (animals And Fungi) Pathway antibodies  Oleate Biosynthesis II (animals And Fungi) Pathway Diagram
 Palmitate Biosynthesis Pathway antibodies  Palmitate Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >4 publications with ACOT2 and Fatty Liver
 Weight Gain Antibodies  >1 publications with ACOT2 and Weight Gain
 Disease Models, Animal Antibodies  >1 publications with ACOT2 and Disease Models, Animal
 Abnormalities, Drug-Induced Antibodies  >1 publications with ACOT2 and Abnormalities, Drug-Induced
 Weight Loss Antibodies  >1 publications with ACOT2 and Weight Loss
 Hyperplasia Antibodies  >1 publications with ACOT2 and Hyperplasia
Organs/Tissues associated with anti-ACOT2 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with ACOT2 and Liver
 Heart Antibodies  >5 publications with ACOT2 and Heart
 Muscle Antibodies  >4 publications with ACOT2 and Muscle
 Adrenal Gland Antibodies  >4 publications with ACOT2 and Adrenal Gland
 Adipose Tissue Antibodies  >3 publications with ACOT2 and Adipose Tissue
 Blood Antibodies  >3 publications with ACOT2 and Blood
 Connective Tissue Antibodies  >3 publications with ACOT2 and Connective Tissue
 Brain Antibodies  >2 publications with ACOT2 and Brain
 Ovary Antibodies  >1 publications with ACOT2 and Ovary
 Testis Antibodies  >1 publications with ACOT2 and Testis
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