Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ACOX1 rightarrow Polyclonal ACOX1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • 40S ribosomal protein S11 (Rps11) Recombinant Protein
 • NALP10 (NLRP10) Antibody
 • BSG Antibody
 • chromatin modifying protein 5 (CHMP5) Antibody
 • Goat F(ab')2 Anti-Mouse IgG3 (gamma 3 chain specific) Secondary Antibody
 • Coagulation Factor XI (F11) ELISA Kit
 • TNIP1 Antibody
 • ADAMTS18 Blocking Peptide
 • POLDIP2 Antibody
 • Integrin alpha-V (ITGAV) ELISA Kit
 • Angiotensin 2 Receptor 1 Antibody (AT2R1) ELISA Kit
 • 3-oxo-5-Alpha steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit
 • CD30 Antibody
 • 24-dehydrocholesterol reductase (DHCR24) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ACOX1 antibody :: Rabbit ACOX1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9128138
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACOX1, Polyclonal Antibody

 Also Known As   

ACOX1 Polyclonal Antibody

 Product Gene Name   

anti-ACOX1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    264470
 3D Structure    ModBase 3D Structure for Q15067
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Affinity Purification
Section Bar
 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human ACOX1
Section Bar
 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-ACOX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-ACOX1 antibody

   The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
 Applications Tested/Suitable for anti-ACOX1 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ACOX1 antibody    WB 1:500 - 1:2000
IHC 1:50 - 1:200
Section Bar
 Western Blot (WB) of anti-ACOX1 antibody    Western blot analysis of extract of various cells, using ACOX1 antibody.
anti-ACOX1 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ACOX1. It may not necessarily be applicable to this product.
 NCBI GI #    297206874
 NCBI GeneID    51
 NCBI Accession #    NP_001171968.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001185039.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q15067 [Other Products]
 UniProt Secondary Accession #    Q12863; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31; A8K6X8; A8KAA0; B4DK61; F5GYQ8 [Other Products]
 UniProt Related Accession #    Q15067 [Other Products]
 Molecular Weight    74kDa
Table BarTOPTable Bar
 NCBI Official Full Name    peroxisomal acyl-coenzyme A oxidase 1 isoform c
 NCBI Official Synonym Full Names    acyl-CoA oxidase 1, palmitoyl
 NCBI Official Symbol    ACOX1 [Similar Products]
 NCBI Official Synonym Symbols   
ACOX; SCOX; PALMCOX
[Similar Products]
 NCBI Protein Information    peroxisomal acyl-coenzyme A oxidase 1
 UniProt Protein Name    Peroxisomal acyl-coenzyme A oxidase 1
 UniProt Synonym Protein Names   
Palmitoyl-CoA oxidase; Straight-chain acyl-CoA oxidase; SCOX
 Protein Family    Peroxisomal acyl-coenzyme A oxidase
 UniProt Gene Name    ACOX1 [Similar Products]
 UniProt Synonym Gene Names    ACOX; AOX; SCOX [Similar Products]
 UniProt Entry Name    ACOX1_HUMAN
Section Bar
 NCBI Summary for ACOX1    The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for ACOX1    ACOX1: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA. Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD); also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.3.3.6; Oxidoreductase; Lipid Metabolism - fatty acid; Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - alpha-linolenic acid

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: nucleoplasm; peroxisomal membrane; peroxisomal matrix; intracellular membrane-bound organelle; membrane; mitochondrion; plasma membrane; nucleolus; peroxisome; nucleus

Molecular Function: palmitoyl-CoA oxidase activity; acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; FAD binding; protein N-terminus binding; fatty acid binding; PDZ domain binding; receptor binding

Biological Process: peroxisome fission; fatty acid beta-oxidation using acyl-CoA oxidase; generation of precursor metabolites and energy; very-long-chain fatty acid metabolic process; unsaturated fatty acid metabolic process; lipid homeostasis; spermatogenesis; fatty acid oxidation; lipid metabolic process; cellular lipid metabolic process; prostaglandin metabolic process

Disease: Peroxisomal Acyl-coa Oxidase Deficiency
Table BarTOPTable Bar
 Research Articles on ACOX1    1. Because patients with AOx deficiency suffer from more severe symptoms than those with X-ALD, accumulation of VLC-PUFA and/or reduction of DHA may be associated with the severity of peroxisomal diseases.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products related to ACOX1 Polyclonal Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS1444741  Recombinant Phascolarctos cinereus Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1), partial  MBS2544213  Rabbit anti Human ACOX1  Monoclonal Antibody
 MBS9356238  Rabbit Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1) ELISA Kit  MBS9360049  Bovine Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1) ELISA Kit
 MBS8225192  ACOX1 siRNA (Mouse)  MBS9352010  Porcine Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1) ELISA Kit
 MBS9213971  ACOX1 Antibody (C-term)  MBS9128138  ACOX1 Polyclonal Antibody
 MBS6006308  ACOX1 (Peroxisomal Acyl-coenzyme A Oxidase 1, AOX, Acyl-coenzyme A Oxidase 1, Peroxisomal, Palmitoyl...  MBS1450379  Recombinant Mouse Peroxisomal acyl-coenzyme A oxidase 1 (Acox1)
Products associated with anti-ACOX1 antibodyPathways associated with anti-ACOX1 antibody
 Reference Product  PubMed Publications
 CPT1A antibody  >17 publications with ACOX1 and CPT1A
 PPARA antibody  >8 publications with ACOX1 and PPARA
 EHHADH antibody  >5 publications with ACOX1 and EHHADH
 ACAA1 antibody  >3 publications with ACOX1 and ACAA1
 ACAA2 antibody  >2 publications with ACOX1 and ACAA2
 ACAT1 antibody  >1 publications with ACOX1 and ACAT1
 HSD17B4 antibody  >1 publications with ACOX1 and HSD17B4
 Products by Pathway  Pathway Diagram
 Beta-oxidation Of Very Long Chain Fatty Acids Pathway antibodies  Beta-oxidation Of Very Long Chain Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with anti-ACOX1 antibodyOrgans/Tissues associated with anti-ACOX1 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >61 publications with ACOX1 and Fatty Liver
 Liver Diseases Antibodies  >26 publications with ACOX1 and Liver Diseases
 Inflammation Antibodies  >16 publications with ACOX1 and Inflammation
 Weight Gain Antibodies  >9 publications with ACOX1 and Weight Gain
 Liver Neoplasms Antibodies  >8 publications with ACOX1 and Liver Neoplasms
 Insulin Resistance Antibodies  >6 publications with ACOX1 and Insulin Resistance
 Carcinoma, Hepatocellular Antibodies  >5 publications with ACOX1 and Carcinoma, Hepatocellular
 Hyperinsulinism Antibodies  >4 publications with ACOX1 and Hyperinsulinism
 Non-alcoholic Fatty Liver Disease Antibodies  >4 publications with ACOX1 and Non-alcoholic Fatty Liver Disease
 Atherosclerosis Antibodies  >4 publications with ACOX1 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >85 publications with ACOX1 and Liver
 Blood Antibodies  >23 publications with ACOX1 and Blood
 Adipose Tissue Antibodies  >15 publications with ACOX1 and Adipose Tissue
 Brain Antibodies  >13 publications with ACOX1 and Brain
 Muscle Antibodies  >12 publications with ACOX1 and Muscle
 Kidney Antibodies  >10 publications with ACOX1 and Kidney
 Connective Tissue Antibodies  >9 publications with ACOX1 and Connective Tissue
 Intestine Antibodies  >4 publications with ACOX1 and Intestine
 Thyroid Antibodies  >4 publications with ACOX1 and Thyroid
 Embryonic Tissue Antibodies  >3 publications with ACOX1 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions