AAH17053
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69,575 Da
NCBI Official Full Name
ACOX3 protein
NCBI Official Synonym Full Names
acyl-CoA oxidase 3, pristanoyl
NCBI Protein Information
peroxisomal acyl-coenzyme A oxidase 3
UniProt Protein Name
Peroxisomal acyl-coenzyme A oxidase 3
UniProt Synonym Protein Names
Branched-chain acyl-CoA oxidase; BRCACox; Pristanoyl-CoA oxidase
UniProt Synonym Gene Names
UniProt Entry Name
ACOX3_HUMAN
NCBI Summary for ACOX3
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008]
UniProt Comments for ACOX3
ACOX3: Oxidizes the CoA-esters of 2-methyl-branched fatty acids. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.3.3.6; Lipid Metabolism - fatty acid; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase
Chromosomal Location of Human Ortholog: 4p15.3
Cellular Component: peroxisomal matrix; membrane; mitochondrion; peroxisome
Molecular Function: acyl-CoA dehydrogenase activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding
Biological Process: fatty acid beta-oxidation using acyl-CoA oxidase; cellular lipid metabolic process
Research Articles on ACOX3
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Products associated with anti-ACOX3 antibody
Pathways associated with anti-ACOX3 antibody
Diseases associated with anti-ACOX3 antibody
Organs/Tissues associated with anti-ACOX3 antibody
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