NP_001010845.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,223 Da
NCBI Official Synonym Full Names
acyl-CoA synthetase medium chain family member 2A
NCBI Protein Information
acyl-coenzyme A synthetase ACSM2A, mitochondrial
UniProt Protein Name
Acyl-coenzyme A synthetase ACSM2A, mitochondrial
UniProt Synonym Protein Names
Acyl-CoA synthetase medium-chain family member 2A; Butyrate--CoA ligase 2A; Butyryl-coenzyme A synthetase 2A; Middle-chain acyl-CoA synthetase 2A
UniProt Synonym Gene Names
NCBI Summary for ACSM2A
This gene encodes a mitochondrial acyl-coenzyme A synthetase that is specific for medium chain fatty acids. These enzymes catalyze fatty acid activation, the first step of fatty acid metabolism, through the transfer of acyl-CoA. These enzymes also participate in the glycine conjugation pathway in the detoxification of xenobiotics such as benzoate and ibuprofen. Expression levels of this gene in the kidney may be correlated with kidney function. This gene and its paralog ACSM2B (Gene ID: 348158), both present on chromosome 16, likely arose from a chromosomal duplication event. [provided by RefSeq, May 2017]
UniProt Comments for ACSM2A
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C4 to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro) ().
Product References and Citations for anti-ACSM2A antibody
(1) Kochan, G., Pilka, E.S., von Delft, F., et al. Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A. J. Mol. Biol. 388 (5), 997-1008 (2009).
Research Articles on ACSM2A
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Pathways associated with anti-ACSM2A antibody
Diseases associated with anti-ACSM2A antibody
Organs/Tissues associated with anti-ACSM2A antibody
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