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anti-ACTB antibody :: Rabbit ACTB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2522935 anti-ACTB antibody
Unit / Price
0.06 mL  /  $195 +1 FREE 8GB USB
0.12 mL  /  $270 +1 FREE 8GB USB
0.2 mL  /  $435 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACTB, Polyclonal Antibody

 Also Known As   

ACTB Antibody

 Product Synonym Names    PS1TP5BP1
 Product Gene Name   

anti-ACTB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    102630
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Zebrafish
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 Purity/Purification    Antigen affinity purification
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 Immunogen    Fusion protein of ACTB
 Calculated Molecular Weight: 375aa; 42kd   
 Buffer    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130656 / sc-130657
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ACTB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ACTB antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for ACTB. It may not necessarily be applicable to this product.
 NCBI GI #    117167827
 NCBI GeneID    60
 NCBI Accession #    AAI13037.1 [Other Products]
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 UniProt Secondary Accession #    P02570; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5 [Other Products]
 UniProt Related Accession #    P60709 [Other Products]
 Molecular Weight    41,737 Da
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 NCBI Official Full Name    ACTB protein, partial
 NCBI Official Synonym Full Names    actin, beta
 NCBI Official Symbol    ACTB [Similar Products]
 NCBI Official Synonym Symbols   
BRWS1; PS1TP5BP1
[Similar Products]
 NCBI Protein Information    actin, cytoplasmic 1; PS1TP5-binding protein 1; beta cytoskeletal actin
 UniProt Protein Name    Actin, cytoplasmic 1
 UniProt Synonym Protein Names   
Beta-actinActin, cytoplasmic 1, N-terminally processed
 Protein Family    Actin
 UniProt Gene Name    ACTB [Similar Products]
 UniProt Entry Name    ACTB_HUMAN
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 NCBI Summary for ACTB    This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ACTB    ACTB: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCET2. Belongs to the actin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: cortical cytoskeleton; extracellular space; NuA4 histone acetyltransferase complex; focal adhesion; protein complex; postsynaptic density; ribonucleoprotein complex; cytosol; nucleoplasm; cytoskeleton; membrane; axon; cytoplasm; nuclear chromatin; plasma membrane

Molecular Function: protein binding; nucleosomal DNA binding; structural constituent of cytoskeleton; kinesin binding; Tat protein binding; nitric-oxide synthase binding; protein kinase binding; ATP binding

Biological Process: axon guidance; intercellular junction assembly and maintenance; establishment and/or maintenance of chromatin architecture; protein folding; 'de novo' posttranslational protein folding; retinal homeostasis; cellular protein metabolic process; substantia nigra development; ATP-dependent chromatin remodeling; ephrin receptor signaling pathway; innate immune response; vascular endothelial growth factor receptor signaling pathway; cell motility; blood coagulation

Disease: Dystonia, Juvenile-onset; Baraitser-winter Syndrome 1
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 Research Articles on ACTB    1. Mutations in ACTB cause a distinctly more severe phenotype than ACTG1 mutations in Baraitser-Winter syndrome.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ACTB antibodyDiseases associated with anti-ACTB antibody
 Products by Pathway  Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >50 publications with ACTB and Carcinoma
 Brain Diseases Antibodies  >23 publications with ACTB and Brain Diseases
 Liver Diseases Antibodies  >23 publications with ACTB and Liver Diseases
 Disease Models, Animal Antibodies  >20 publications with ACTB and Disease Models, Animal
 Lung Diseases Antibodies  >16 publications with ACTB and Lung Diseases
 Kidney Diseases Antibodies  >16 publications with ACTB and Kidney Diseases
 Necrosis Antibodies  >16 publications with ACTB and Necrosis
 Inflammation Antibodies  >13 publications with ACTB and Inflammation
 Liver Neoplasms Antibodies  >12 publications with ACTB and Liver Neoplasms
 Heart Diseases Antibodies  >11 publications with ACTB and Heart Diseases
Organs/Tissues associated with anti-ACTB antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >72 publications with ACTB and Blood
 Brain Antibodies  >56 publications with ACTB and Brain
 Liver Antibodies  >53 publications with ACTB and Liver
 Muscle Antibodies  >50 publications with ACTB and Muscle
 Kidney Antibodies  >35 publications with ACTB and Kidney
 Lung Antibodies  >30 publications with ACTB and Lung
 Bone Antibodies  >27 publications with ACTB and Bone
 Heart Antibodies  >25 publications with ACTB and Heart
 Connective Tissue Antibodies  >21 publications with ACTB and Connective Tissue
 Embryonic Tissue Antibodies  >20 publications with ACTB and Embryonic Tissue
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