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anti-ACTG2 antibody :: Rabbit anti-Human ACTG2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6007405 anti-ACTG2 antibody
Unit / Price
0.2 mL  /  $580 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACTG2, Polyclonal Antibody

 Also Known As   

ACTG2, CT (ACTG2, ACTA3, ACTL3, ACTSG, Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin)

 Product Synonym Names    Anti -ACTG2, CT (ACTG2, ACTA3, ACTL3, ACTSG, Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin)
 Product Gene Name   

anti-ACTG2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (74120093..74146780). Location: 2p13.1
 OMIM    102545
 3D Structure    ModBase 3D Structure for P63267
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Human
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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 Immunogen    ACTG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human ACTG2.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-ACTG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-ACTG2 antibody

   Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.
 Product Categories/Family for anti-ACTG2 antibody    Antibodies; Abs to Actin Related Proteins
 Applications Tested/Suitable for anti-ACTG2 antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ACTG2 antibody    Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
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NCBI/Uniprot data below describe general gene information for ACTG2. It may not necessarily be applicable to this product.
 NCBI GI #    315570273
 NCBI GeneID    72
 NCBI Accession #    NP_001186822.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199893.1 [Other Products]
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 UniProt Primary Accession #    P63267 [Other Products]
 UniProt Secondary Accession #    P12718; Q504R1; Q6FI22; B2R7E7; B4E315; D6W5H8; E9PG30 [Other Products]
 UniProt Related Accession #    P63267 [Other Products]
 Molecular Weight    41,877 Da [Similar Products]
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 NCBI Official Full Name    actin, gamma-enteric smooth muscle isoform 2
 NCBI Official Synonym Full Names    actin, gamma 2, smooth muscle, enteric
 NCBI Official Symbol    ACTG2 [Similar Products]
 NCBI Official Synonym Symbols   
ACT; ACTE; ACTA3; ACTL3; ACTSG
[Similar Products]
 NCBI Protein Information    actin, gamma-enteric smooth muscle; alpha-actin 3; alpha-actin-3; gamma-2-actin; actin-like protein; smooth muscle gamma actin; smooth muscle gamma-actin
 UniProt Protein Name    Actin, gamma-enteric smooth muscle
 UniProt Synonym Protein Names   
Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin
 Protein Family    Actin
 UniProt Gene Name    ACTG2 [Similar Products]
 UniProt Synonym Gene Names    ACTA3; ACTL3; ACTSG [Similar Products]
 UniProt Entry Name    ACTH_HUMAN
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 NCBI Summary for ACTG2    Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
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 UniProt Comments for ACTG2    ACTG2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.

Protein type: Motility/polarity/chemotaxis; Contractile; Cytoskeletal

Chromosomal Location of Human Ortholog: 2p13.1

Cellular Component: extracellular space; cytoskeleton; cytosol

Molecular Function: ATP binding

Biological Process: muscle contraction

Disease: Visceral Myopathy
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 Research Articles on ACTG2    1. The R148S variant in ACTG2 as a cause of autosomal dominant familial visceral myopathy in one family.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ACTG2 antibodyPathways associated with anti-ACTG2 antibody
 Reference Product  PubMed Publications
 ACTA2 antibody  >2 publications with ACTG2 and ACTA2
 CNN1 antibody  >1 publications with ACTG2 and CNN1
 Products by Pathway  Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Smooth Muscle Contraction Pathway antibodies  Smooth Muscle Contraction Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram
Diseases associated with anti-ACTG2 antibodyOrgans/Tissues associated with anti-ACTG2 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with ACTG2 and Neoplasms
 Adenocarcinoma Antibodies  >3 publications with ACTG2 and Adenocarcinoma
 Liver Neoplasms Antibodies  >2 publications with ACTG2 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with ACTG2 and Disease Models, Animal
 Lung Neoplasms Antibodies  >1 publications with ACTG2 and Lung Neoplasms
 Anemia Antibodies  >1 publications with ACTG2 and Anemia
 Neoplasm Metastasis Antibodies  >1 publications with ACTG2 and Neoplasm Metastasis
 Carcinoma, Hepatocellular Antibodies  >1 publications with ACTG2 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >1 publications with ACTG2 and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with ACTG2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >6 publications with ACTG2 and Muscle
 Liver Antibodies  >3 publications with ACTG2 and Liver
 Lung Antibodies  >3 publications with ACTG2 and Lung
 Connective Tissue Antibodies  >2 publications with ACTG2 and Connective Tissue
 Eye Antibodies  >1 publications with ACTG2 and Eye
 Pancreas Antibodies  >1 publications with ACTG2 and Pancreas
 Embryonic Tissue Antibodies  >1 publications with ACTG2 and Embryonic Tissue
 Testis Antibodies  >1 publications with ACTG2 and Testis
 Prostate Antibodies  >1 publications with ACTG2 and Prostate
 Bone Antibodies  >1 publications with ACTG2 and Bone
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