NP_060051.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,807 Da
NCBI Official Full Name
neuronal acetylcholine receptor subunit alpha-9
NCBI Official Synonym Full Names
cholinergic receptor nicotinic alpha 9 subunit
NCBI Protein Information
neuronal acetylcholine receptor subunit alpha-9
UniProt Protein Name
Neuronal acetylcholine receptor subunit alpha-9
UniProt Synonym Protein Names
Nicotinic acetylcholine receptor subunit alpha-9; NACHR alpha-9
UniProt Synonym Gene Names
NCBI Summary for AChRalpha9
This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. [provided by RefSeq, Feb 2012]
UniProt Comments for AChRalpha9
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840).
Research Articles on AChRalpha9
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Products associated with anti-AChRalpha9 antibody
Pathways associated with anti-AChRalpha9 antibody
Diseases associated with anti-AChRalpha9 antibody
Organs/Tissues associated with anti-AChRalpha9 antibody
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