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anti-ADAM28 antibody :: Rabbit anti-Human ADAM28 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044181
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAM28, Polyclonal Antibody

★Popular Item★
 Also Known As   

ADAM28 Antibody

 Product Synonym Names    Disintegrin and metalloproteinase domain-containing protein 28; ADAM 28; Epididymal metalloproteinase-like; disintegrin-like; and cysteine-rich protein II; eMDC II; Metalloproteinase-like; disintegrin-like; and cysteine-rich protein L; MDC-L; ADAM28; ADAM23; MDCL
 Product Gene Name   

anti-ADAM28 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606188
 3D Structure    ModBase 3D Structure for Q9UKQ2
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Disintegrin and metalloproteinase domain-containing protein 28 protein (199-440AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26012
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ADAM28 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ADAM28 antibody

   May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
 Applications Tested/Suitable for anti-ADAM28 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-ADAM28 antibody    Western blot
All lanes: ADAM28 antibody IgG at 5.6ug/ml+ PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 88,62 kDa
Observed band size: 87 kDa

anti-ADAM28 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ADAM28 antibody    Immunohistochemistry of paraffin-embedded human breast cancer using MBS7044181 at dilution 1:100
anti-ADAM28 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ADAM28. It may not necessarily be applicable to this product.
 NCBI GI #    748983380
 NCBI GeneID    10863
 NCBI Accession #    NP_001291280.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001304351.1 [Other Products]
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 UniProt Primary Accession #    Q9UKQ2 [Other Products]
 UniProt Secondary Accession #    Q9Y339; Q9Y3S0; B2RMV5 [Other Products]
 UniProt Related Accession #    Q9UKQ2 [Other Products]
 Molecular Weight    61,232 Da
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 NCBI Official Full Name    disintegrin and metalloproteinase domain-containing protein 28 isoform 4 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase domain 28
 NCBI Official Symbol    ADAM28 [Similar Products]
 NCBI Official Synonym Symbols   
MDCL; MDC-L; eMDCII; ADAM 28; eMDC II
[Similar Products]
 NCBI Protein Information    disintegrin and metalloproteinase domain-containing protein 28
 UniProt Protein Name    Disintegrin and metalloproteinase domain-containing protein 28
 UniProt Synonym Protein Names   
Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; eMDC II; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; MDC-L
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAM28 [Similar Products]
 UniProt Synonym Gene Names    ADAM23; MDCL; ADAM 28; eMDC II; MDC-L [Similar Products]
 UniProt Entry Name    ADA28_HUMAN
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 NCBI Summary for ADAM28    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
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 UniProt Comments for ADAM28    ADAM28: May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Protease; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 8p21.2

Molecular Function: metallopeptidase activity

Biological Process: spermatogenesis
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 Research Articles on ADAM28    1. The results of this study suggest that these proteins play important roles in pulmonary inflammatory reactions elicited against etiological viral agents.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADAM28 antibodyDiseases associated with anti-ADAM28 antibody
 Reference Product  PubMed Publications
 LGI1 antibody  >1 publications with ADAM28 and LGI1
 ITGB1 antibody  >1 publications with ADAM28 and ITGB1
 ITGA4 antibody  >1 publications with ADAM28 and ITGA4
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >12 publications with ADAM28 and Lung Neoplasms
 Lung Diseases Antibodies  >10 publications with ADAM28 and Lung Diseases
 Breast Neoplasms Antibodies  >7 publications with ADAM28 and Breast Neoplasms
 Inflammation Antibodies  >5 publications with ADAM28 and Inflammation
 Neoplasm Metastasis Antibodies  >4 publications with ADAM28 and Neoplasm Metastasis
 Skin Diseases Antibodies  >4 publications with ADAM28 and Skin Diseases
 Neoplasms, Experimental Antibodies  >4 publications with ADAM28 and Neoplasms, Experimental
 Necrosis Antibodies  >3 publications with ADAM28 and Necrosis
 Fibrosis Antibodies  >2 publications with ADAM28 and Fibrosis
 Atherosclerosis Antibodies  >2 publications with ADAM28 and Atherosclerosis
Organs/Tissues associated with anti-ADAM28 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >19 publications with ADAM28 and Blood
 Lung Antibodies  >17 publications with ADAM28 and Lung
 Mouth Antibodies  >11 publications with ADAM28 and Mouth
 Lymph Node Antibodies  >8 publications with ADAM28 and Lymph Node
 Lymph Antibodies  >8 publications with ADAM28 and Lymph
 Connective Tissue Antibodies  >3 publications with ADAM28 and Connective Tissue
 Kidney Antibodies  >3 publications with ADAM28 and Kidney
 Bladder Antibodies  >3 publications with ADAM28 and Bladder
 Muscle Antibodies  >2 publications with ADAM28 and Muscle
 Embryonic Tissue Antibodies  >2 publications with ADAM28 and Embryonic Tissue
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