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anti-ADAMTS14 antibody :: Rabbit anti-Human ADAMTS14 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2527871
Immunohistochemistry (IHC)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAMTS14, Polyclonal Antibody

★Popular Item★
 Also Known As   

ADAMTS14 Polyclonal Antibody

 Product Synonym Names    A disintegrin and metalloproteinase with thrombospondin motifs 14,ADAM TS14,ADAMTS 14,ADAMTS14,EC 3.4.24,FLJ32820
 Product Gene Name   

anti-ADAMTS14 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2527871 Technical Datasheet    Technical Datasheet PDF
 OMIM    607506
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Affinity purification
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 Immunogen    Synthetic peptide of human ADAMTS14
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ADAMTS14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ADAMTS14 antibody

   This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This gene is highly similar to two family members, ADAMTS2 and ADAMTS3, in its sequence and gene structure, and the encoded protein shares the aminoprocollagen peptidase activity with the protein products encoded by ADAMTS2 and ADAMTS3. Various transcript variants of this gene have been identified. They result from the use of two different promoters and transcription initiation sites as well as alternative splicing sites. The full length nature of some transcripts has not been defined.
 Product Categories/Family for anti-ADAMTS14 antibody    Cell biology
 Applications Tested/Suitable for anti-ADAMTS14 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-ADAMTS14 antibody    IHC: 1:25-1:100
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 Immunohistochemistry (IHC) of anti-ADAMTS14 antibody    Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ADAMTS14 Polyclonal Antibody at dilution 1:50
anti-ADAMTS14 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ADAMTS14. It may not necessarily be applicable to this product.
 NCBI GI #    110611167
 NCBI GeneID    140766
 NCBI Accession #    NP_542453 [Other Products]
 NCBI GenBank Nucleotide #    NM_139155.2 [Other Products]
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 UniProt Secondary Accession #    Q5T4G0; Q5T4G1; Q8TE55; Q8TEY8 [Other Products]
 UniProt Related Accession #    Q8WXS8 [Other Products]
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform 1 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 14
 NCBI Official Symbol    ADAMTS14 [Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 14; ADAM-TS 14; ADAM-TS14; ADAMTS-14; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 14; metalloprotease-disintegrin protease
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 14
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    ADAMTS14 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 14; ADAM-TS14; ADAMTS-14 [Similar Products]
 UniProt Entry Name    ATS14_HUMAN
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 NCBI Summary for ADAMTS14    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This gene is highly similar to two family members, ADAMTS2 and ADAMTS3, in its sequence and gene structure, and the encoded protein shares the aminoprocollagen peptidase activity with the protein products encoded by ADAMTS2 and ADAMTS3. Various transcript variants of this gene have been identified. They result from the use of two different promoters and transcription initiation sites as well as alternative splicing sites. The full length nature of some transcripts has not been defined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAMTS14    ADAMTS14: Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. 4 isoforms of the human protein are produced by alternative promoter.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; EC 3.4.24.-; Protease

Chromosomal Location of Human Ortholog: 10q21

Cellular Component: proteinaceous extracellular matrix; extracellular region

Molecular Function: zinc ion binding; metalloendopeptidase activity

Biological Process: collagen catabolic process; extracellular matrix organization and biogenesis; collagen fibril organization; proteolysis
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 Research Articles on ADAMTS14    1. Carriage of the ADAMTS14 rs4747096 GG variant appears to delay onset of the injury in Achilles tendon pathology.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADAMTS14 antibodyPathways associated with anti-ADAMTS14 antibody
 Reference Product  PubMed Publications
 PCOLCE2 antibody  >1 publications with ADAMTS14 and PCOLCE2
 PCOLCE antibody  >1 publications with ADAMTS14 and PCOLCE
 Products by Pathway  Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
Diseases associated with anti-ADAMTS14 antibodyOrgans/Tissues associated with anti-ADAMTS14 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with ADAMTS14 and Carcinoma
 Bone Diseases Antibodies  >1 publications with ADAMTS14 and Bone Diseases
 Lung Neoplasms Antibodies  >1 publications with ADAMTS14 and Lung Neoplasms
 Liver Neoplasms Antibodies  >1 publications with ADAMTS14 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with ADAMTS14 and Liver Neoplasms, Experimental
 Neoplasm Metastasis Antibodies  >1 publications with ADAMTS14 and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >1 publications with ADAMTS14 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with ADAMTS14 and Bone
 Lung Antibodies  >3 publications with ADAMTS14 and Lung
 Placenta Antibodies  >2 publications with ADAMTS14 and Placenta
 Embryonic Tissue Antibodies  >2 publications with ADAMTS14 and Embryonic Tissue
 Skin Antibodies  >2 publications with ADAMTS14 and Skin
 Brain Antibodies  >2 publications with ADAMTS14 and Brain
 Mixed Antibodies  >1 publications with ADAMTS14 and Mixed
 Eye Antibodies  >1 publications with ADAMTS14 and Eye
 Kidney Antibodies  >1 publications with ADAMTS14 and Kidney
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