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anti-ADAMTS6 antibody :: Rabbit anti-Human ADAMTS6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9210131
Western Blot (WB)
Unit / Price
0.08 mL  /  $155 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAMTS6, Polyclonal Antibody

 Also Known As   

ADAMTS6 Antibody (N-Term)

 Product Synonym Names    A disintegrin and metalloproteinase with thrombospondin motifs 6; ADAM-TS 6; ADAM-TS6; ADAMTS-6; 3424-; ADAMTS6
 Product Gene Name   

anti-ADAMTS6 antibody

[Similar Products]
 Antibody/Peptide Pairs    ADAMTS6 peptide (MBS9229966) is used for blocking the activity of ADAMTS6 antibody (MBS9210131)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605008
 3D Structure    ModBase 3D Structure for Q9UKP5
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 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This ADAMTS6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 118-151 amino acids from the region of human ADAMTS6.
 Purity/Purification    Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
 Concentration    Vial Concentration: 0.5 (lot specific)
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 Antigen Source    HUMAN
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-ADAMTS6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ADAMTS6 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-ADAMTS6 antibody    WB~~1:2000
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 Western Blot (WB) of anti-ADAMTS6 antibody    All lanes : Anti-ADAMTS6 Antibody (N-Term) at 1:2000 dilution
Lane 1: Hela whole cell lysates
Lane 2: HT-1080 whole cell lysates

Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution

Predicted band size : 125 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
anti-ADAMTS6 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ADAMTS6. It may not necessarily be applicable to this product.
 NCBI GI #    64276808
 NCBI GeneID    11174
 NCBI Accession #    NP_922932.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_197941.2 [Other Products]
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 UniProt Primary Accession #    Q9UKP5 [Other Products]
 UniProt Secondary Accession #    Q59EX6; Q5IR87; Q5IR88; Q5IR89; Q68DL1 [Other Products]
 UniProt Related Accession #    Q9UKP5 [Other Products]
 Molecular Weight    125273
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 6 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 6
 NCBI Official Symbol    ADAMTS6 [Similar Products]
 NCBI Official Synonym Symbols   
ADAM-TS6; ADAMTS-6; ADAM-TS 6
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 6
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 6
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    ADAMTS6 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 6; ADAM-TS6; ADAMTS-6 [Similar Products]
 UniProt Entry Name    ATS6_HUMAN
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 NCBI Summary for ADAMTS6    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAMTS6    ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

Protein type: Secreted, signal peptide; Protease; Secreted; Motility/polarity/chemotaxis; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 5q12

Cellular Component: proteinaceous extracellular matrix

Molecular Function: zinc ion binding; metallopeptidase activity; metalloendopeptidase activity

Biological Process: proteolysis
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Product References and Citations for anti-ADAMTS6 antibody

   Hurskainen T.L.,et al.J. Biol. Chem. 274:25555-25563(1999).
Bevitt D.J.,et al.Gene 359:99-110(2005).
Schmutz J.,et al.Nature 431:268-274(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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 Research Articles on ADAMTS6    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADAMTS6 antibodyPathways associated with anti-ADAMTS6 antibody
 Reference Product  PubMed Publications
 FURIN antibody  >2 publications with ADAMTS6 and FURIN
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
Diseases associated with anti-ADAMTS6 antibodyOrgans/Tissues associated with anti-ADAMTS6 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >4 publications with ADAMTS6 and Necrosis
 Inflammation Antibodies  >3 publications with ADAMTS6 and Inflammation
 Fibrosis Antibodies  >2 publications with ADAMTS6 and Fibrosis
 Central Nervous System Diseases Antibodies  >2 publications with ADAMTS6 and Central Nervous System Diseases
 Nervous System Diseases Antibodies  >2 publications with ADAMTS6 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with ADAMTS6 and Brain Diseases
 Hemorrhagic Disorders Antibodies  >1 publications with ADAMTS6 and Hemorrhagic Disorders
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with ADAMTS6 and Eye
 Embryonic Tissue Antibodies  >2 publications with ADAMTS6 and Embryonic Tissue
 Lung Antibodies  >2 publications with ADAMTS6 and Lung
 Heart Antibodies  >1 publications with ADAMTS6 and Heart
 Muscle Antibodies  >1 publications with ADAMTS6 and Muscle
 Liver Antibodies  >1 publications with ADAMTS6 and Liver
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