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anti-ADAMTSL5 antibody :: Chicken ADAMTSL5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150785
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAMTSL5, Polyclonal Antibody

 Also Known As   

ADAMTSL5 Antibody

 Product Synonym Names    ADAMTSL5; THSD6; THSD6; ADAMTS-like protein 5; Thrombospondin type-1 domain-containing protein 6; ADAMTSL-5; ADAMTS-like 5
 Product Gene Name   

anti-ADAMTSL5 antibody

[Similar Products]
 Antibody/Peptide Pairs    ADAMTSL5 peptide (MBS151994) is used for blocking the activity of ADAMTSL5 antibody (MBS150785)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q6ZMM2
 Clonality    Polyclonal
 Isotype    IgY
 Host    Chicken
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    ADAMTSL5 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    ADAMTSL5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ADAMTSL5.
 Buffer    ADAMTSL5 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    ADAMTSL5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-ADAMTSL5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ADAMTSL5 antibody

   ADAMTSL5 Antibody: ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
 Applications Tested/Suitable for anti-ADAMTSL5 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-ADAMTSL5 antibody    ADAMTSL5 antibody can be used for detection of ADAMTSL5 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
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 Western Blot (WB) of anti-ADAMTSL5 antibody    Western blot analysis of ADAMTSL5 in human skeletal muscle tissue lysate with ADAMTSL5 antibody at 1 μg/mL.
anti-ADAMTSL5 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-ADAMTSL5 antibody    Immunofluorescence of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 20 μg/mL.
anti-ADAMTSL5 antibody Immunofluorescence (IF) image
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 Immunohistochemistry (IHC) of anti-ADAMTSL5 antibody    Immunohistochemistry of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 5 μg/mL.
anti-ADAMTSL5 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ADAMTSL5. It may not necessarily be applicable to this product.
 NCBI GI #    226442878
 NCBI GeneID    339366
 NCBI Accession #    NP_998769 [Other Products]
 NCBI GenBank Nucleotide #    NM_213604.2 [Other Products]
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 UniProt Primary Accession #    Q6ZMM2 [Other Products]
 UniProt Secondary Accession #    Q8IW95; B4DXK7 [Other Products]
 UniProt Related Accession #    Q6ZMM2 [Other Products]
 Molecular Weight    53,171 Da
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 NCBI Official Full Name    ADAMTS-like protein 5
 NCBI Official Synonym Full Names    ADAMTS-like 5
 NCBI Official Symbol    ADAMTSL5 [Similar Products]
 NCBI Official Synonym Symbols   
THSD6
[Similar Products]
 NCBI Protein Information    ADAMTS-like protein 5; ADAMTSL-5; thrombospondin, type I, domain containing 6; thrombospondin type-1 domain-containing protein 6
 UniProt Protein Name    ADAMTS-like protein 5
 UniProt Synonym Protein Names   
Thrombospondin type-1 domain-containing protein 6
 Protein Family    ADAMTS-like protein
 UniProt Gene Name    ADAMTSL5 [Similar Products]
 UniProt Synonym Gene Names    THSD6; ADAMTSL-5 [Similar Products]
 UniProt Entry Name    ATL5_HUMAN
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 UniProt Comments for ADAMTSL5    ADAMTSL5: May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM). Interacts with heparin, FBN1 and FBN2. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Secreted; Secreted, signal peptide; Protease; Extracellular matrix

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: proteinaceous extracellular matrix; microfibril; extracellular region

Molecular Function: heparin binding; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis
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 Research Articles on ADAMTSL5    1. ADAMTSL5 could have a role in modulating microfibril functions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ADAMTSL5 antibody
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
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