|
| Product Name
|
|
ADAP1, Polyclonal Antibody
|
| Also Known As
|
|
ADAP1 Polyclonal Antibody
|
| Product Synonym Names
|
|
GCS1L, CENTA1, p42IP4
|
| Product Gene Name
|
|
|
[Similar Products]
|
| Research Use Only
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
 TOP
|
|
| OMIM
|
|
608114
|
|
| Clonality
|
|
Polyclonal
|
| Isotype
|
|
IgG
|
| Host
|
|
Rabbit
|
| Species Reactivity
|
|
Human, Mouse, Rat
|
|
|
| Purity/Purification
|
|
Antigen affinity purification
|
| Concentration
|
|
0.8mg/mL (lot specific)
|
|
|
| Immunogen
|
|
Recombinant protein of human ADAP1
|
| Calculated Molecular Weight: 43kDa
|
|
|
| Buffer
|
|
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
|
|
|
| Preparation and Storage
|
|
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
|
| ISO Certification
|
|
Manufactured in an ISO 9001:2008 Certified Laboratory.
|
| Other Notes
|
|
Small volumes of anti-ADAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
|
|
TOP
|
|
|
|
|
Arf-GAP with dual PH domain-containing protein 1 is a protein that in humans is encoded by the ADAP1 gene. GTPase-activating protein for the ADP ribosylation factor family. Binds phosphatidylinositol 3, 4, 5-trisphosphate (PtdInsP3) and inositol 1, 3, 4, 5-tetrakisphosphate (InsP4).
|
|
| Applications Tested/Suitable for anti-ADAP1 antibody
|
|
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
|
| Application Notes for anti-ADAP1 antibody
|
|
WB: 1:200-1:1000
IHC: 1:100-1:200
|
|
|
| Western Blot (WB) of anti-ADAP1 antibody
|
|
Western Blot analysis of Mouse brain tissue using ADAP1 Polyclonal Antibody at dilution of 1:500
|
|
|
| Immunohistochemistry (IHC) of anti-ADAP1 antibody
|
|
Immunohistochemistry of paraffin-embedded Human colon cancer using ADAP1 Polyclonal Antibody at dilution of 1:60
|
|
|
| Immunohistochemistry (IHC) of anti-ADAP1 antibody
|
|
Immunohistochemistry of paraffin-embedded Human lung cancer using ADAP1 Polyclonal Antibody at dilution of 1:60
|
|
TOP
|
|
| NCBI/Uniprot data below describe general gene information for ADAP1. It may not necessarily be applicable to this product. |
| NCBI GI #
|
|
546232233
|
| NCBI GeneID
|
|
11033
|
| NCBI Accession #
|
|
NP_001271240.1
|
[Other Products]
|
| NCBI GenBank Nucleotide #
|
|
NM_001284311.1
|
[Other Products]
|
|
|
| UniProt Secondary Accession #
|
|
A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4
|
[Other Products]
|
| UniProt Related Accession #
|
|
O75689
|
[Other Products]
|
| Molecular Weight
|
|
35,353 Da
|
|
TOP
|
| NCBI Official Full Name
|
|
arf-GAP with dual PH domain-containing protein 1 isoform 4
|
| NCBI Official Synonym Full Names
|
|
ArfGAP with dual PH domains 1
|
| NCBI Official Symbol
|
|
ADAP1
|
[Similar Products]
|
| NCBI Official Synonym Symbols
|
|
GCS1L; CENTA1; p42IP4
|
[Similar Products]
|
| NCBI Protein Information
|
|
arf-GAP with dual PH domain-containing protein 1; centaurin, alpha 1; centaurin-alpha; centaurin-alpha-1; cnt-a1; putative MAPK-activating protein PM25
|
| UniProt Protein Name
|
|
Arf-GAP with dual PH domain-containing protein 1
|
| UniProt Synonym Protein Names
|
|
Centaurin-alpha-1; Cnt-a1; Putative MAPK-activating protein PM25
|
| Protein Family
|
|
Arf-GAP with dual PH domain-containing protein
|
| UniProt Gene Name
|
|
ADAP1
|
[Similar Products]
|
| UniProt Synonym Gene Names
|
|
CENTA1; Cnt-a1
|
[Similar Products]
|
| UniProt Entry Name
|
|
ADAP1_HUMAN
|
|
|
| UniProt Comments for ADAP1
|
|
CENTA1: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Protein type: GAPs, ARF; GAPs
Chromosomal Location of Human Ortholog: 7p22.3
Cellular Component: cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; phosphatidylinositol-3,4,5-triphosphate binding; zinc ion binding; inositol 1,3,4,5 tetrakisphosphate binding
Biological Process: regulation of GTPase activity; cell surface receptor linked signal transduction; positive regulation of GTPase activity
|
|
TOP
|
|
| Research Articles on ADAP1
|
|
1. SH-SY5Y cells, stably transfected with GFP-tagged-p42(IP4), show an enhanced NRD protein expression already at an earlier time point after retinoic acid stimulation.
|
|
TOP
|
| Precautions
|
|
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
|
| Disclaimer
|
|
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
|
|
TOP
|
|
| Products associated with anti-ADAP1 antibody | Pathways associated with anti-ADAP1 antibody |
|
|
|
| Diseases associated with anti-ADAP1 antibody | Organs/Tissues associated with anti-ADAP1 antibody |
|
|
|
|
|
|
TOP
|
Antibody 
