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anti-ADAP1 antibody :: Rabbit ADAP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2521877
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADAP1, Polyclonal Antibody

 Also Known As   

ADAP1 Polyclonal Antibody

 Product Synonym Names    GCS1L, CENTA1, p42IP4
 Product Gene Name   

anti-ADAP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608114
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    0.8mg/mL (lot specific)
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 Immunogen    Recombinant protein of human ADAP1
 Calculated Molecular Weight: 43kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-ADAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-ADAP1 antibody

   Arf-GAP with dual PH domain-containing protein 1 is a protein that in humans is encoded by the ADAP1 gene. GTPase-activating protein for the ADP ribosylation factor family. Binds phosphatidylinositol 3, 4, 5-trisphosphate (PtdInsP3) and inositol 1, 3, 4, 5-tetrakisphosphate (InsP4).
 Applications Tested/Suitable for anti-ADAP1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ADAP1 antibody    WB: 1:200-1:1000
IHC: 1:100-1:200
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 Immunohistochemistry (IHC) of anti-ADAP1 antibody    Immunohistochemistry of Human colon cancer using ADAP1 Polyclonal Antibody at dilution of 1:60
anti-ADAP1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ADAP1 antibody    Immunohistochemistry of Human lung cancer using ADAP1 Polyclonal Antibody at dilution of 1:60
anti-ADAP1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ADAP1. It may not necessarily be applicable to this product.
 NCBI GI #    546232233
 NCBI GeneID    11033
 NCBI Accession #    NP_001271240.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001284311.1 [Other Products]
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 UniProt Secondary Accession #    A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4 [Other Products]
 UniProt Related Accession #    O75689 [Other Products]
 Molecular Weight    35,353 Da
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 NCBI Official Full Name    arf-GAP with dual PH domain-containing protein 1 isoform 4
 NCBI Official Synonym Full Names    ArfGAP with dual PH domains 1
 NCBI Official Symbol    ADAP1 [Similar Products]
 NCBI Official Synonym Symbols   
GCS1L; CENTA1; p42IP4
[Similar Products]
 NCBI Protein Information    arf-GAP with dual PH domain-containing protein 1; centaurin, alpha 1; centaurin-alpha; centaurin-alpha-1; cnt-a1; putative MAPK-activating protein PM25
 UniProt Protein Name    Arf-GAP with dual PH domain-containing protein 1
 UniProt Synonym Protein Names   
Centaurin-alpha-1; Cnt-a1; Putative MAPK-activating protein PM25
 Protein Family    Arf-GAP with dual PH domain-containing protein
 UniProt Gene Name    ADAP1 [Similar Products]
 UniProt Synonym Gene Names    CENTA1; Cnt-a1 [Similar Products]
 UniProt Entry Name    ADAP1_HUMAN
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 UniProt Comments for ADAP1    CENTA1: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).

Protein type: GAPs, ARF; GAPs

Chromosomal Location of Human Ortholog: 7p22.3

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; phosphatidylinositol-3,4,5-triphosphate binding; zinc ion binding; inositol 1,3,4,5 tetrakisphosphate binding

Biological Process: regulation of GTPase activity; cell surface receptor linked signal transduction; positive regulation of GTPase activity
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 Research Articles on ADAP1    1. SH-SY5Y cells, stably transfected with GFP-tagged-p42(IP4), show an enhanced NRD protein expression already at an earlier time point after retinoic acid stimulation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADAP1 antibodyPathways associated with anti-ADAP1 antibody
 Reference Product  PubMed Publications
 ARF6 antibody  >6 publications with ADAP1 and ARF6
 KIF13B antibody  >3 publications with ADAP1 and KIF13B
 Products by Pathway  Pathway Diagram
 Arf6 Signaling Events Pathway antibodies  Arf6 Signaling Events Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
Diseases associated with anti-ADAP1 antibodyOrgans/Tissues associated with anti-ADAP1 antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >4 publications with ADAP1 and Brain Diseases
 Nervous System Diseases Antibodies  >3 publications with ADAP1 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >32 publications with ADAP1 and Nerve
 Brain Antibodies  >23 publications with ADAP1 and Brain
 Kidney Antibodies  >3 publications with ADAP1 and Kidney
 Blood Antibodies  >2 publications with ADAP1 and Blood
 Embryonic Tissue Antibodies  >2 publications with ADAP1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with ADAP1 and Ovary
 Connective Tissue Antibodies  >1 publications with ADAP1 and Connective Tissue
 Heart Antibodies  >1 publications with ADAP1 and Heart
 Adipose Tissue Antibodies  >1 publications with ADAP1 and Adipose Tissue
 Lung Antibodies  >1 publications with ADAP1 and Lung
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