NP_001268697.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,440 Da
NCBI Official Full Name
adenylate cyclase type 1 isoform 2
NCBI Official Synonym Full Names
adenylate cyclase 1 (brain)
NCBI Official Synonym Symbols
NCBI Protein Information
adenylate cyclase type 1; 3',5'-cyclic AMP synthetase; ATP pyrophosphate-lyase 1; Ca(2+)/calmodulin-activated adenylyl cyclase; adenyl cyclase; adenylate cyclase type I; adenylyl cyclase 1
UniProt Protein Name
Adenylate cyclase type 1
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
UniProt Entry Name
ADCY1_HUMAN
NCBI Summary for ADCY1
This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for ADCY1
ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.
Protein type: Nucleotide Metabolism - purine; Membrane protein, integral; Membrane protein, multi-pass; EC 4.6.1.1; Transporter; Adenylyl cyclase; Transporter, aquaporin family; Lyase
Chromosomal Location of Human Ortholog: 7p12.3
Cellular Component: cytoplasm; plasma membrane; integral to membrane; nucleus
Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding
Biological Process: response to drug; epidermal growth factor receptor signaling pathway; circadian rhythm; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; response to lithium ion; activation of protein kinase A; regulation of circadian rhythm; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; axonogenesis; long-term memory; phospholipase C activation; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport
Disease: Deafness, Autosomal Recessive 44
Research Articles on ADCY1
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Products associated with anti-ADCY1 antibody
Pathways associated with anti-ADCY1 antibody
Diseases associated with anti-ADCY1 antibody
Organs/Tissues associated with anti-ADCY1 antibody
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