NP_004027.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
128,960 Da
NCBI Official Full Name
adenylate cyclase type 3
NCBI Official Synonym Full Names
adenylate cyclase 3
NCBI Official Synonym Symbols
NCBI Protein Information
adenylate cyclase type 3; AC-III; adenylyl cyclase 3; ATP pyrophosphate-lyase 3; adenylate cyclase type III; adenylyl cyclase, type III; adenylate cyclase, olfactive type
UniProt Protein Name
Adenylate cyclase type 3
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 3; Adenylate cyclase type III; AC-III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3; AC3
UniProt Synonym Gene Names
UniProt Entry Name
ADCY3_HUMAN
NCBI Summary for ADCY3
This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. [provided by RefSeq, Jul 2008]
UniProt Comments for ADCY3
Function: Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.
Catalytic activity: ATP = 3',5'-cyclic AMP + diphosphate.
Cofactor: Binds 2 magnesium ions per subunit
By similarity.
Enzyme regulation: Activated by calcium/calmodulin.
Subcellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
Sequence similarities: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.Contains 2 guanylate cyclase domains.
Product References and Citations for anti-ADCY3 antibody
1. Fuchs JL, Schwark HD. Neuronal primary cilia: a review. Cell Biol Int. 28:111-8 (2004).2. Louvi A and Grove EA. Cilia in the CNS: the quiet organelle claims center stage. Neuron 69:1046-1060 (2011).
Research Articles on ADCY3
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Products associated with anti-ADCY3 antibody
Pathways associated with anti-ADCY3 antibody
Diseases associated with anti-ADCY3 antibody
Organs/Tissues associated with anti-ADCY3 antibody
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