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anti-ADCYAP1R1 antibody :: Rabbit ADCYAP1R1 / PAC1 Receptor Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS246921
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADCYAP1R1 / PAC1 Receptor, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human ADCYAP1R1 / PAC1 Receptor

 Product Synonym Names    Anti-ADCYAP1R1 / PAC1 Receptor Antibody (C-Terminus) IHC-plus; PAC1; Pac1 receptor; Pac1 receptors; PAC1-R; PACAP receptor 1; Pacap specific receptor; PACAP-R-1; PACAP/VIP receptors; PACAP1 receptor; PACAP Receptor; Pacap receptor type 1; Pacap type 1 receptor; PACAP type I receptor; PACAPR; PAC1R; Human ADCYAP1R1; PAC1 Receptor
 Product Gene Name   

anti-ADCYAP1R1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    102981
 3D Structure    ModBase 3D Structure for P41586
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Bat, Gibbon, Chicken, Dog, Xenopus, Gorilla, Human, Monkey
Predicted Reactivity: Zebrafish (at least 90% immunogen sequence identity)
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 Specificity    Human ADCYAP1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 17 amino acid peptide from C-terminus of human ADCYAP1R1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Chicken, Lizard, Xenopus (100%).
 Immunogen Type    Synthetic peptide
 Immunogen    ADCYAP1R1 / PAC1 Receptor antibody was raised against synthetic 17 amino acid peptide from C-terminus of human ADCYAP1R1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Chicken, Lizard, Xenopus (100%); Stickleback, Pufferfish, Zebrafish (94%); Mouse, Rat, Hamster, Elephant, Bovine, Horse, Pig (88%).
 Antigen Modification    C-Terminus
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-ADCYAP1R1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ADCYAP1R1 antibody

   The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems.
 Product Categories/Family for anti-ADCYAP1R1 antibody    Family: GPCR
Subfamily: Vasoactive intestinal polypeptide
 Applications Tested/Suitable for anti-ADCYAP1R1 antibody   

Immunohistochemistry (IHC - Paraffin)

 Application Notes for anti-ADCYAP1R1 antibody    IHC-P (15 ug/ml)
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 Immunohistochemistry (IHC) of anti-ADCYAP1R1 antibody    Anti-ADCYAP1R1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ADCYAP1R1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ADCYAP1R1 antibody    Anti-ADCYAP1R1 / PAC1 Receptor antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-ADCYAP1R1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ADCYAP1R1. It may not necessarily be applicable to this product.
 NCBI GI #    29171759
 NCBI GeneID    117
 NCBI Accession #    NP_001109.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001118.4 [Other Products]
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 UniProt Primary Accession #    P41586 [Other Products]
 UniProt Secondary Accession #    Q17S10; A8K1Y1; B7ZLA7; B8ZZK3 [Other Products]
 UniProt Related Accession #    P41586 [Other Products]
 Molecular Weight    46,957 Da
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 NCBI Official Full Name    pituitary adenylate cyclase-activating polypeptide type I receptor isoform 3
 NCBI Official Synonym Full Names    adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
 NCBI Official Symbol    ADCYAP1R1 [Similar Products]
 NCBI Official Synonym Symbols   
PAC1; PAC1R; PACAPR; PACAPRI
[Similar Products]
 NCBI Protein Information    pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
 UniProt Protein Name    Pituitary adenylate cyclase-activating polypeptide type I receptor
 Protein Family    Pituitary adenylate cyclase-activating polypeptide type I receptor
 UniProt Gene Name    ADCYAP1R1 [Similar Products]
 UniProt Synonym Gene Names    PACAP type I receptor; PACAP-R-1; PACAP-R1 [Similar Products]
 UniProt Entry Name    PACR_HUMAN
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 NCBI Summary for ADCYAP1R1    This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
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 UniProt Comments for ADCYAP1R1    ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2

Chromosomal Location of Human Ortholog: 7p14

Cellular Component: neuron projection; tight junction; cell surface; rough endoplasmic reticulum; integral to plasma membrane; plasma membrane; caveola; endosome; receptor complex

Molecular Function: ADP-ribosylation factor binding; neuropeptide binding; protein binding; vasoactive intestinal polypeptide receptor activity; receptor activity; adenylate cyclase binding

Biological Process: response to drug; development of primary female sexual characteristics; nerve growth factor receptor signaling pathway; adenylate cyclase activation; response to estradiol stimulus; G-protein coupled receptor protein signaling pathway; cAMP-mediated signaling; response to ethanol; cell surface receptor linked signal transduction; phospholipase C activation; spermatogenesis; cell differentiation; multicellular organismal response to stress; transmembrane receptor protein tyrosine kinase signaling pathway
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 Research Articles on ADCYAP1R1    1. PAC1/PACAP receptor endocytosis contributes to ERK acktivation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADCYAP1R1 antibodyPathways associated with anti-ADCYAP1R1 antibody
 Reference Product  PubMed Publications
 ADCYAP1 antibody  >104 publications with ADCYAP1R1 and ADCYAP1
 CRH antibody  >2 publications with ADCYAP1R1 and CRH
 GHRH antibody  >2 publications with ADCYAP1R1 and GHRH
 POMC antibody  >1 publications with ADCYAP1R1 and POMC
 Products by Pathway  Pathway Diagram
 Activation Of TRKA Receptors Pathway antibodies  Activation Of TRKA Receptors Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
Diseases associated with anti-ADCYAP1R1 antibodyOrgans/Tissues associated with anti-ADCYAP1R1 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >6 publications with ADCYAP1R1 and Breast Neoplasms
 Inflammation Antibodies  >5 publications with ADCYAP1R1 and Inflammation
 Kidney Diseases Antibodies  >3 publications with ADCYAP1R1 and Kidney Diseases
 Disease Models, Animal Antibodies  >2 publications with ADCYAP1R1 and Disease Models, Animal
 Learning Disorders Antibodies  >2 publications with ADCYAP1R1 and Learning Disorders
 Hyperplasia Antibodies  >2 publications with ADCYAP1R1 and Hyperplasia
 Brain Injuries Antibodies  >2 publications with ADCYAP1R1 and Brain Injuries
 Liver Neoplasms, Experimental Antibodies  >2 publications with ADCYAP1R1 and Liver Neoplasms, Experimental
 Liver Diseases Antibodies  >2 publications with ADCYAP1R1 and Liver Diseases
 Hypertrophy Antibodies  >2 publications with ADCYAP1R1 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >76 publications with ADCYAP1R1 and Brain
 Nerve Antibodies  >28 publications with ADCYAP1R1 and Nerve
 Pituitary Gland Antibodies  >26 publications with ADCYAP1R1 and Pituitary Gland
 Blood Antibodies  >15 publications with ADCYAP1R1 and Blood
 Ganglia Antibodies  >14 publications with ADCYAP1R1 and Ganglia
 Muscle Antibodies  >12 publications with ADCYAP1R1 and Muscle
 Adrenal Gland Antibodies  >11 publications with ADCYAP1R1 and Adrenal Gland
 Lung Antibodies  >10 publications with ADCYAP1R1 and Lung
 Kidney Antibodies  >6 publications with ADCYAP1R1 and Kidney
 Intestine Antibodies  >5 publications with ADCYAP1R1 and Intestine
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