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anti-ADH1A antibody :: Rabbit ADH1A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2519564
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADH1A, Polyclonal Antibody

 Also Known As   

ADH1A Polyclonal Antibody

 Product Synonym Names    ADH1
 Product Gene Name   

anti-ADH1A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    103700
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    1mg/mL (lot specific)
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 Immunogen    Recombinant protein of human ADH1A
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ADH1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ADH1A antibody

   This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
 Applications Tested/Suitable for anti-ADH1A antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-ADH1A antibody    IHC: 1:25-1:100
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 Immunohistochemistry (IHC) of anti-ADH1A antibody    Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ADH1A Polyclonal Antibody at dilution 1:25
anti-ADH1A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ADH1A antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ADH1A Polyclonal Antibody at dilution 1:25
anti-ADH1A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ADH1A. It may not necessarily be applicable to this product.
 NCBI GI #    4501929
 NCBI GeneID    124
 NCBI Accession #    NP_000658.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000667.3 [Other Products]
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 UniProt Secondary Accession #    Q17R68; A8K3E3 [Other Products]
 UniProt Related Accession #    P07327 [Other Products]
 Molecular Weight    39,859 Da
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 NCBI Official Full Name    alcohol dehydrogenase 1A
 NCBI Official Synonym Full Names    alcohol dehydrogenase 1A (class I), alpha polypeptide
 NCBI Official Symbol    ADH1A [Similar Products]
 NCBI Official Synonym Symbols   
ADH1
[Similar Products]
 NCBI Protein Information    alcohol dehydrogenase 1A; ADH, alpha subunit; alcohol dehydrogenase 1 (class I), alpha polypeptide; alcohol dehydrogenase subunit alpha; aldehyde reductase
 UniProt Protein Name    Alcohol dehydrogenase 1A
 UniProt Synonym Protein Names   
Alcohol dehydrogenase subunit alpha
 UniProt Gene Name    ADH1A [Similar Products]
 UniProt Synonym Gene Names    ADH1 [Similar Products]
 UniProt Entry Name    ADH1A_HUMAN
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 NCBI Summary for ADH1A    This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]
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 UniProt Comments for ADH1A    ADH1A: a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Protein type: Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.1; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine; Transcription regulation; Cofactor and Vitamin Metabolism - retinol; Oxidoreductase

Chromosomal Location of Human Ortholog: 4q23

Cellular Component: cytosol

Molecular Function: protein binding; zinc ion binding; alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent

Biological Process: xenobiotic metabolic process; alcohol metabolic process; ethanol oxidation; drug metabolic process
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 Research Articles on ADH1A    1. Data indicate that the up-regulation of aldehyde dehydrogenase-1 (ALDH1) after neoadjuvant chemotherapy (NAC) predicts poor survival in locally advanced breast cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ADH1A antibodyDiseases associated with anti-ADH1A antibody
 Products by Pathway  Pathway Diagram
 Abacavir Metabolism Pathway antibodies  Abacavir Metabolism Pathway Diagram
 Abacavir Transport And Metabolism Pathway antibodies  Abacavir Transport And Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway antibodies  Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway Diagram
 Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway antibodies  Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway Diagram
 Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway antibodies  Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway Diagram
 Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway antibodies  Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway Diagram
 Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway antibodies  Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >3 publications with ADH1A and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with ADH1A and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with ADH1A and Carcinoma, Hepatocellular
 Ovarian Neoplasms Antibodies  >1 publications with ADH1A and Ovarian Neoplasms
 Recurrence Antibodies  >1 publications with ADH1A and Recurrence
 Necrosis Antibodies  >1 publications with ADH1A and Necrosis
 Poisoning Antibodies  >1 publications with ADH1A and Poisoning
Organs/Tissues associated with anti-ADH1A antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >10 publications with ADH1A and Liver
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