NP_001651.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ADP-ribosylation factor 4
NCBI Official Synonym Full Names
ADP ribosylation factor 4
NCBI Official Synonym Symbols
NCBI Protein Information
ADP-ribosylation factor 4
UniProt Protein Name
ADP-ribosylation factor 4
UniProt Synonym Gene Names
UniProt Entry Name
ARF4_HUMAN
UniProt Comments for ARF4
ARF4: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.
Protein type: G protein; G protein, monomeric; G protein, monomeric, ARF; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3p14.3
Cellular Component: cytosol; dendritic spine; extracellular matrix; membrane
Molecular Function: ARF guanyl-nucleotide exchange factor activity; epidermal growth factor receptor binding; GTP binding; GTPase activity; protein binding
Biological Process: cell migration; ER to Golgi vesicle-mediated transport; negative regulation of apoptosis; phospholipase D activation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid ADP-ribosylation; retrograde vesicle-mediated transport, Golgi to ER
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Pathways associated with anti-ARF4 antibody
Diseases associated with anti-ARF4 antibody
Organs/Tissues associated with anti-ARF4 antibody
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