AAH89043.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ADP-ribosylation factor-like 4C
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 4C
NCBI Official Synonym Symbols
NCBI Protein Information
ADP-ribosylation factor-like protein 4C; ADP-ribosylation factor-like 7; ADP ribosylation factor-like protein 7; ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK
UniProt Protein Name
ADP-ribosylation factor-like protein 4C
UniProt Synonym Protein Names
ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK
UniProt Synonym Gene Names
UniProt Entry Name
ARL4C_HUMAN
NCBI Summary for ARL4C
ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008]
UniProt Comments for ARL4C
ARL4C: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP- bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. Belongs to the small GTPase superfamily. Arf family.
Protein type: G protein, monomeric, ARF; G protein; G protein, monomeric
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: cytoplasm; plasma membrane; nucleus; filopodium
Molecular Function: GTPase activity; protein binding; GTP binding; alpha-tubulin binding
Biological Process: metabolic process; small GTPase mediated signal transduction; endocytic recycling
Research Articles on ARL4C
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Products associated with anti-ARL4C antibody
Diseases associated with anti-ARL4C antibody
Organs/Tissues associated with anti-ARL4C antibody
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