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anti-AGTPBP1 antibody :: Rabbit anti-Human, mouse AGTPBP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9213580
Western Blot (WB)
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AGTPBP1, Polyclonal Antibody

 Also Known As   

AGTPBP1 Antibody (N-term)

 Product Synonym Names    Cytosolic carboxypeptidase 1; 3417-; ATP/GTP-binding protein 1; Nervous system nuclear protein induced by axotomy protein 1 homolog; AGTPBP1; CCP1; KIAA1035; NNA1
 Product Gene Name   

anti-AGTPBP1 antibody

[Similar Products]
 Antibody/Peptide Pairs    AGTPBP1 peptide (MBS9222675) is used for blocking the activity of AGTPBP1 antibody (MBS9213580)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    363-392
 OMIM    606830
 3D Structure    ModBase 3D Structure for Q9UPW5
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 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human, mouse
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 Specificity    This AGTPBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-392 amino acids from the N-terminal region of human AGTPBP1.
 Purity/Purification    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
 Concentration    Vial Concentration: 0.35 (lot specific)
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 Antigen Type    Synthetic Peptide
 Antigen Source    HUMAN
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-AGTPBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-AGTPBP1 antibody

   NNA1 is a zinc carboxypeptidase that contains nuclear
localization signals and an ATP/GTP-binding motif that was
initially cloned from regenerating spinal cord neurons of the
mouse.
 Product Categories/Family for anti-AGTPBP1 antibody    Cell Biology; Signal Transduction
 Applications Tested/Suitable for anti-AGTPBP1 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-AGTPBP1 antibody    WB~~1:1000
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 Western Blot (WB) of anti-AGTPBP1 antibody    AGTPBP1 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the AGTPBP1 antibody detected the AGTPBP1 protein (arrow).
anti-AGTPBP1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for AGTPBP1. It may not necessarily be applicable to this product.
 NCBI GI #    170763513
 NCBI GeneID    23287
 NCBI Accession #    NP_056054.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_015239.2 [Other Products]
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 UniProt Primary Accession #    Q9UPW5 [Other Products]
 UniProt Secondary Accession #    Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; B4DIT6; B4DRZ8 [Other Products]
 UniProt Related Accession #    Q9UPW5 [Other Products]
 Molecular Weight    138448
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 NCBI Official Full Name    cytosolic carboxypeptidase 1 isoform b
 NCBI Official Synonym Full Names    ATP/GTP binding protein 1
 NCBI Official Symbol    AGTPBP1 [Similar Products]
 NCBI Official Synonym Symbols   
CCP1; NNA1
[Similar Products]
 NCBI Protein Information    cytosolic carboxypeptidase 1
 UniProt Protein Name    Cytosolic carboxypeptidase 1
 UniProt Synonym Protein Names   
ATP/GTP-binding protein 1; Nervous system nuclear protein induced by axotomy protein 1 homolog
 UniProt Gene Name    AGTPBP1 [Similar Products]
 UniProt Synonym Gene Names    CCP1; KIAA1035; NNA1 [Similar Products]
 UniProt Entry Name    CBPC1_HUMAN
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 NCBI Summary for AGTPBP1    NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002]
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 UniProt Comments for AGTPBP1    Nna1: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Interacts with MYLK. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.17.-; Protease

Chromosomal Location of Human Ortholog: 9q21.33

Cellular Component: mitochondrion; cytoplasm; cytosol; nucleus

Molecular Function: tubulin binding; zinc ion binding; metallocarboxypeptidase activity

Biological Process: mitochondrion organization and biogenesis; olfactory bulb development; neuromuscular process; cerebellar Purkinje cell differentiation; eye photoreceptor cell differentiation; proteolysis
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Product References and Citations for anti-AGTPBP1 antibody

   Lim, J., et al. Cell 125(4):801-814(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Fernandez-Gonzalez, A., et al. Science 295(5561):1904-1906(2002)
Harris, A., et al. Mol. Cell. Neurosci. 16(5):578-596(2000)
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 Research Articles on AGTPBP1    1. Data indicate that a functional nuclear export signals (NESs) in CCP1 that mediates direct binding to the export receptor CRM1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-AGTPBP1 antibodyOrgans/Tissues associated with anti-AGTPBP1 antibody
 Disease Name  Pubmed Publications
 Nerve Degeneration Antibodies  >14 publications with AGTPBP1 and Nerve Degeneration
 Nervous System Diseases Antibodies  >9 publications with AGTPBP1 and Nervous System Diseases
 Brain Diseases Antibodies  >7 publications with AGTPBP1 and Brain Diseases
 Disease Models, Animal Antibodies  >6 publications with AGTPBP1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23 publications with AGTPBP1 and Brain
 Eye Antibodies  >4 publications with AGTPBP1 and Eye
 Blood Antibodies  >2 publications with AGTPBP1 and Blood
 Testis Antibodies  >2 publications with AGTPBP1 and Testis
 Bone Antibodies  >1 publications with AGTPBP1 and Bone
 Vascular Antibodies  >1 publications with AGTPBP1 and Vascular
 Embryonic Tissue Antibodies  >1 publications with AGTPBP1 and Embryonic Tissue
 Bone Marrow Antibodies  >1 publications with AGTPBP1 and Bone Marrow
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