NP_001015891.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 20 Observed MW: 20
NCBI Official Full Name
adenylate kinase isoenzyme 6 isoform c
NCBI Official Synonym Full Names
adenylate kinase 6
NCBI Official Synonym Symbols
CIP; CINAP; AD-004; hCINAP; CGI-137 [Similar Products]
NCBI Protein Information
adenylate kinase isoenzyme 6
UniProt Protein Name
Adenylate kinase isoenzyme 6
UniProt Synonym Protein Names
Adrenal gland protein AD-004; Coilin-interacting nuclear ATPase protein
UniProt Synonym Gene Names
UniProt Entry Name
KAD6_HUMAN
NCBI Summary for AK6
This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for AK6
TAFII31 iso2: a component of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is essential for mediating regulation of RNA polymerase transcription. TAFII31 binds to p53, the basal transcription factor GTF2B, and the acidic transactivator viral protein 16 (VP16). It is a coactivator for P53.
Protein type: Acetyltransferase; EC 2.7.4.3; Kinase, other; Transcription initiation complex; DNA-binding
Chromosomal Location of Human Ortholog: 5q13.2
Cellular Component: nucleoplasm; PCAF complex; transcription factor TFIID complex
Molecular Function: ATPase binding; DNA binding; histone acetyltransferase activity; p53 binding; protein binding; protein heterodimerization activity; transcription activator binding; transcription coactivator activity
Biological Process: box C/D snoRNP assembly; establishment and/or maintenance of chromatin architecture; gene expression; negative regulation of apoptosis; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cell growth; positive regulation of transcription from RNA polymerase II promoter; protein stabilization; response to DNA damage stimulus; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction
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Pathways associated with anti-AK6 antibody
Diseases associated with anti-AK6 antibody
Organs/Tissues associated with anti-AK6 antibody
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