Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow AKR1A1 rightarrow Polyclonal AKR1A1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Beta-casein (CSN2) Recombinant Protein
 • OGT Antibody
 • STXBP1 Antibody
 • KLK12 Antibody
 • inducible nitric oxide synthase (iNOS) ELISA Kit
 • Transglutaminase 2, Tissue (TGM2) ELISA Kit
 • free-beta Rat chorionicgonadotrophin (F-betahCG) ELISA Kit
 • S100 calcium binding protein A1 (S100A1) ELISA Kit
 • BMP-7 Antibody
 • RASGEF1A Antibody
 • adrenomedullin (ADM) ELISA Kit
 • bone morphogenetic protein receptor, type IA (BMPR1A) ELISA Kit
 • Actin, alpha cardiac muscle 1 (ACTC1) Recombinant Protein
 • OR2I1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-AKR1A1 antibody :: Rabbit anti-Human, Mouse AKR1A1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7047648
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AKR1A1, Polyclonal Antibody

★Popular Item★
 Also Known As   

AKR1A1 Antibody

 Product Synonym Names    Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1; AKR1A1; ALDR1; ALR
 Product Gene Name   

anti-AKR1A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    J04794 mRNA
 3D Structure    ModBase 3D Structure for P14550
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
Section Bar
 Immunogen    Recombinant Human Alcohol dehydrogenase [NADP(+)] protein (2-325AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, PH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161328 / sc-161329
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-AKR1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-AKR1A1 antibody

   Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1, 2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
 Applications Tested/Suitable for anti-AKR1A1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-AKR1A1 antibody    WB: 1: 2000-1: 10000
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
Section Bar
 Western Blot (WB) of anti-AKR1A1 antibody    Western Blot
Positive WB detected in:Mouse liver tissue,Mouse kidney tissue,Mouse stomach tissue
All lanes: Akr1a1 antibody at 2.8ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 37 kDa
Observed band size: 37,23 kDa

anti-AKR1A1 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-AKR1A1 antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7047648 at dilution of 1:100
anti-AKR1A1 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-AKR1A1 antibody    Immunofluorescent analysis of Hela cells using MBS7047648 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-AKR1A1 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for AKR1A1. It may not necessarily be applicable to this product.
 NCBI GI #    320202988
 NCBI GeneID    10327
 NCBI Accession #    NP_001189342.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001202413.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P14550 [Other Products]
 UniProt Secondary Accession #    Q6IAZ4; A8KAL8; D3DQ04 [Other Products]
 UniProt Related Accession #    P14550 [Other Products]
 Molecular Weight    36,573 Da
Table BarTOPTable Bar
 NCBI Official Full Name    alcohol dehydrogenase
 NCBI Official Synonym Full Names    aldo-keto reductase family 1 member A1
 NCBI Official Symbol    AKR1A1 [Similar Products]
 NCBI Official Synonym Symbols   
ALR; ARM; DD3; ALDR1; HEL-S-6
[Similar Products]
 NCBI Protein Information    alcohol dehydrogenase [NADP(+)]
 UniProt Protein Name    Alcohol dehydrogenase [NADP(+)]
 UniProt Synonym Protein Names   
Aldehyde reductase; Aldo-keto reductase family 1 member A1
 Protein Family    Alcohol dehydrogenase
 UniProt Gene Name    AKR1A1 [Similar Products]
 UniProt Synonym Gene Names    ALDR1; ALR [Similar Products]
 UniProt Entry Name    AK1A1_HUMAN
Section Bar
 NCBI Summary for AKR1A1    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011]
Section Bar
 UniProt Comments for AKR1A1    AKR1A1: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Belongs to the aldo/keto reductase family.

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.1.1.2; Lipid Metabolism - glycerolipid; Oxidoreductase

Chromosomal Location of Human Ortholog: 1p33-p32

Cellular Component: cytosol; extracellular space

Molecular Function: aldo-keto reductase activity; electron carrier activity; L-glucuronate reductase activity; protein binding

Biological Process: aldehyde metabolic process; glucose metabolic process; glucuronate catabolic process to xylulose 5-phosphate
Table BarTOPTable Bar
 Research Articles on AKR1A1    1. prostaglandin F synthase activity of human and bovine aldo-keto reductases
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-AKR1A1 antibodyPathways associated with anti-AKR1A1 antibody
 Reference Product  PubMed Publications
 ALDH1A3 antibody  >1 publications with AKR1A1 and ALDH1A3
 Products by Pathway  Pathway Diagram
 Benzo(a)pyrene Metabolism Pathway antibodies  Benzo(a)pyrene Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Catabolism Of Glucuronate To Xylulose-5-phosphate Pathway antibodies  Catabolism Of Glucuronate To Xylulose-5-phosphate Pathway Diagram
 Glucuronate Pathway (uronate Pathway) antibodies  Glucuronate Pathway (uronate Pathway) Diagram
 Glucuronate Pathway (uronate Pathway) antibodies  Glucuronate Pathway (uronate Pathway) Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
Diseases associated with anti-AKR1A1 antibodyOrgans/Tissues associated with anti-AKR1A1 antibody
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >3 publications with AKR1A1 and Lung Neoplasms
 Inflammation Antibodies  >3 publications with AKR1A1 and Inflammation
 Nervous System Diseases Antibodies  >2 publications with AKR1A1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >2 publications with AKR1A1 and Disease Models, Animal
 Cognition Disorders Antibodies  >1 publications with AKR1A1 and Cognition Disorders
 Cell Transformation, Neoplastic Antibodies  >1 publications with AKR1A1 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >1 publications with AKR1A1 and Liver Diseases
 Acute Kidney Injury Antibodies  >1 publications with AKR1A1 and Acute Kidney Injury
 Kidney Diseases Antibodies  >1 publications with AKR1A1 and Kidney Diseases
 Necrosis Antibodies  >1 publications with AKR1A1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >14 publications with AKR1A1 and Liver
 Lung Antibodies  >9 publications with AKR1A1 and Lung
 Kidney Antibodies  >6 publications with AKR1A1 and Kidney
 Blood Antibodies  >5 publications with AKR1A1 and Blood
 Muscle Antibodies  >4 publications with AKR1A1 and Muscle
 Prostate Antibodies  >3 publications with AKR1A1 and Prostate
 Heart Antibodies  >3 publications with AKR1A1 and Heart
 Brain Antibodies  >3 publications with AKR1A1 and Brain
 Intestine Antibodies  >2 publications with AKR1A1 and Intestine
 Testis Antibodies  >2 publications with AKR1A1 and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions