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anti-ALB antibody :: Sheep ALBUMIN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS220435 anti-ALB antibody
Unit / Price
1 mL  /  $415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ALBUMIN, Polyclonal Antibody

★Popular Item★
 Also Known As   

SHEEP ANTI HUMAN ALBUMIN:HRP

 Product Gene Name   

anti-ALB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    103600
 3D Structure    ModBase 3D Structure for P02768
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Sheep
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 Form/Format    HRP
Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
 Concentration    IgG concentration 5.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.05% ProclinTM300
 Buffer Solution    Phosphate buffered saline
 Antiserum Preparation    Antisera to human albumin were raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-ALB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-ALB antibody

   Sheep anti human albumin polyclonal antibody recognizes human albumin, a plasma protein of 66kD.
 Applications Tested/Suitable for anti-ALB antibody   

ELISA (EIA)

 Application Notes for anti-ALB antibody    ELISA: Minimum Dilution: 1/25600; Maximum Dilution: 1/51200
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NCBI/Uniprot data below describe general gene information for ALB. It may not necessarily be applicable to this product.
 NCBI GI #    4502027
 NCBI GeneID    213
 NCBI Accession #    NP_000468.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000477.5 [Other Products]
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 UniProt Primary Accession #    P02768 [Other Products]
 UniProt Secondary Accession #    O95574; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; E7ESS9 [Other Products]
 UniProt Related Accession #    P02768 [Other Products]
 Molecular Weight    45,160 Da [Similar Products]
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 NCBI Official Full Name    serum albumin preproprotein
 NCBI Official Synonym Full Names    albumin
 NCBI Official Symbol    ALB [Similar Products]
 NCBI Official Synonym Symbols   
FDAH; ANALBA; PRO0883; PRO0903; PRO1341
[Similar Products]
 NCBI Protein Information    serum albumin; albumin (32 AA); albumin (AA 34); cell growth inhibiting protein 42; growth-inhibiting protein 20
 UniProt Protein Name    Serum albumin
 Protein Family    Albumin
 UniProt Gene Name    ALB [Similar Products]
 UniProt Entry Name    ALBU_HUMAN
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 NCBI Summary for ALB    Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ALB    albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Carrier

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus

Molecular Function: antioxidant activity; toxin binding; protein binding; enzyme binding; copper ion binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding

Biological Process: platelet activation; receptor-mediated endocytosis; sodium-independent organic anion transport; bile acid metabolic process; maintenance of mitochondrion localization; hemolysis by symbiont of host red blood cells; lipoprotein metabolic process; cellular response to starvation; response to organic substance; bile acid and bile salt transport; response to mercury ion; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis

Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic
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 Research Articles on ALB    1. Data indicate that serum albumin binding site 1 is a preformed binding pocket within the core of subdomain IIA, which comprises six helices of the subdomain and a loop-helix feature (residues 148-154) contributed by subdomain IB.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ALB antibodyDiseases associated with anti-ALB antibody
 Products by Pathway  Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >304 publications with ALB and Kidney Diseases
 Cardiovascular Diseases Antibodies  >208 publications with ALB and Cardiovascular Diseases
 Proteinuria Antibodies  >189 publications with ALB and Proteinuria
 Disease Models, Animal Antibodies  >186 publications with ALB and Disease Models, Animal
 Liver Cirrhosis Antibodies  >168 publications with ALB and Liver Cirrhosis
 Fibrosis Antibodies  >140 publications with ALB and Fibrosis
 Respiratory Tract Diseases Antibodies  >133 publications with ALB and Respiratory Tract Diseases
 Brain Diseases Antibodies  >104 publications with ALB and Brain Diseases
 Kidney Failure, Chronic Antibodies  >83 publications with ALB and Kidney Failure, Chronic
 Heart Diseases Antibodies  >65 publications with ALB and Heart Diseases
Organs/Tissues associated with anti-ALB antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1484 publications with ALB and Blood
 Liver Antibodies  >867 publications with ALB and Liver
 Kidney Antibodies  >402 publications with ALB and Kidney
 Brain Antibodies  >153 publications with ALB and Brain
 Lung Antibodies  >140 publications with ALB and Lung
 Heart Antibodies  >136 publications with ALB and Heart
 Muscle Antibodies  >126 publications with ALB and Muscle
 Spleen Antibodies  >55 publications with ALB and Spleen
 Embryonic Tissue Antibodies  >46 publications with ALB and Embryonic Tissue
 Connective Tissue Antibodies  >37 publications with ALB and Connective Tissue
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