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anti-ALCAM antibody :: Rabbit ALCAM Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2521900
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ALCAM, Polyclonal Antibody

★Popular Item★
 Also Known As   

ALCAM Polyclonal Antibody

 Product Synonym Names    MEMD; CD166
 Product Gene Name   

anti-ALCAM antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601662
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    1.8mg/mL (lot specific)
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 Immunogen    Synthetic peptide of human ALCAM
 Calculated Molecular Weight: 65kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ALCAM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ALCAM antibody

   This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
 Product Categories/Family for anti-ALCAM antibody    Epigenetics
 Applications Tested/Suitable for anti-ALCAM antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ALCAM antibody    WB: 1:200-1:1000
IHC: 1:25-1:100
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 Western Blot (WB) of anti-ALCAM antibody    Western Blot analysis of Mouse thymus tissue using ALCAM Polyclonal Antibody at dilution of 1:200
anti-ALCAM antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ALCAM antibody    Immunohistochemistry of paraffin-embedded Human prostate cancer using ALCAM Polyclonal Antibody at dilution of 1:25
anti-ALCAM antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ALCAM antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer using ALCAM Polyclonal Antibody at dilution of 1:25
anti-ALCAM antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ALCAM. It may not necessarily be applicable to this product.
 NCBI GI #    886258
 NCBI GeneID    214
 NCBI Accession #    AAB59499.1 [Other Products]
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 UniProt Secondary Accession #    O60892; Q1HGM8; Q1HGM9; Q6PEY4; Q6ZS95; B2RNS3; B4DTU0 [Other Products]
 UniProt Related Accession #    Q13740 [Other Products]
 Molecular Weight    33,878 Da
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 NCBI Official Full Name    alcam
 NCBI Official Synonym Full Names    activated leukocyte cell adhesion molecule
 NCBI Official Symbol    ALCAM [Similar Products]
 NCBI Official Synonym Symbols   
MEMD; CD166
[Similar Products]
 NCBI Protein Information    CD166 antigen
 UniProt Protein Name    CD166 antigen
 UniProt Synonym Protein Names   
Activated leukocyte cell adhesion molecule; CD_antigen: CD166
 Protein Family    CD166 antigen
 UniProt Gene Name    ALCAM [Similar Products]
 UniProt Synonym Gene Names    MEMD [Similar Products]
 UniProt Entry Name    CD166_HUMAN
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 NCBI Summary for ALCAM    This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
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 UniProt Comments for ALCAM    ALCAM: Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 3q13.1

Cellular Component: focal adhesion; cell soma; axon; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; receptor binding

Biological Process: axon guidance; motor axon guidance; cell adhesion; signal transduction
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 Research Articles on ALCAM    1. The expression of CD166 using immunohistochemistry in a large cohort of non-small cell lung cancer patients , was evaluated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ALCAM antibodyPathways associated with anti-ALCAM antibody
 Reference Product  PubMed Publications
 CD6 antibody  >64 publications with ALCAM and CD6
 GRASP antibody  >33 publications with ALCAM and GRASP
 EGFR antibody  >5 publications with ALCAM and EGFR
 L1CAM antibody  >5 publications with ALCAM and L1CAM
 NDRG2 antibody  >2 publications with ALCAM and NDRG2
 CD5L antibody  >1 publications with ALCAM and CD5L
 RELA antibody  >1 publications with ALCAM and RELA
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
Diseases associated with anti-ALCAM antibodyOrgans/Tissues associated with anti-ALCAM antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >54 publications with ALCAM and Carcinoma
 Neoplasm Metastasis Antibodies  >38 publications with ALCAM and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >29 publications with ALCAM and Breast Neoplasms
 Adenocarcinoma Antibodies  >25 publications with ALCAM and Adenocarcinoma
 Inflammation Antibodies  >17 publications with ALCAM and Inflammation
 Brain Diseases Antibodies  >16 publications with ALCAM and Brain Diseases
 Necrosis Antibodies  >15 publications with ALCAM and Necrosis
 Prostatic Neoplasms Antibodies  >13 publications with ALCAM and Prostatic Neoplasms
 Liver Diseases Antibodies  >11 publications with ALCAM and Liver Diseases
 Liver Neoplasms Antibodies  >11 publications with ALCAM and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >136 publications with ALCAM and Blood
 Bone Antibodies  >67 publications with ALCAM and Bone
 Nerve Antibodies  >63 publications with ALCAM and Nerve
 Embryonic Tissue Antibodies  >59 publications with ALCAM and Embryonic Tissue
 Brain Antibodies  >56 publications with ALCAM and Brain
 Bone Marrow Antibodies  >48 publications with ALCAM and Bone Marrow
 Vascular Antibodies  >47 publications with ALCAM and Vascular
 Lung Antibodies  >37 publications with ALCAM and Lung
 Liver Antibodies  >24 publications with ALCAM and Liver
 Eye Antibodies  >23 publications with ALCAM and Eye
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