Q5SYQ7
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UniProt Related Accession #
NCBI Official Full Name
aldehyde dehydrogenase 1 family, member A1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member A1
NCBI Official Synonym Symbols
ALDC; ALDH1; PUMB1; ALDH11; RALDH1; ALDH-E1; MGC2318 [Similar Products]
NCBI Protein Information
retinal dehydrogenase 1; ALHDII; RALDH 1; ALDH class 1; OTTHUMP00000021482; acetaldehyde dehydrogenase 1; retinaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic
UniProt Protein Name
Aldehyde dehydrogenase 1 family, member A1
UniProt Entry Name
Q5SYQ7_HUMAN
NCBI Summary for ALDH1A1
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq]
UniProt Comments for ALDH1A1
ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.
Protein type: GAPs; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; Apoptosis; EC 1.2.1.36; GAPs, Ras
Chromosomal Location of Human Ortholog: 9q21.13
Cellular Component: cytoplasm; cytosol
Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; 3-chloroallyl aldehyde dehydrogenase activity; benzaldehyde dehydrogenase (NAD+) activity; retinal dehydrogenase activity
Biological Process: retinol metabolic process; xenobiotic metabolic process; aldehyde metabolic process; ethanol oxidation
Research Articles on ALDH1A1
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Pathways associated with anti-ALDH1A1 antibody
Diseases associated with anti-ALDH1A1 antibody
Organs/Tissues associated with anti-ALDH1A1 antibody
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