Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ALDH1A3 rightarrow Polyclonal ALDH1A3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Formamidase (amiF) Recombinant Protein
 • Collagenase, Type II (Collagenase II) ELISA Kit
 • brain natriuretic peptide, BNP ELISA Kit
 • Hepcidin 25 (Hepc25) ELISA Kit
 • Transforming Growth Factor Beta 1 (TGFb1) ELISA Kit
 • IL23A - IL-23 p19 Antibody
 • Ephrin B2 (EFNB2) ELISA Kit
 • N-Cadherin (CDH2) Antibody
 • O-acetyl transferase (OAC) Recombinant Protein
 • GSDMD Antibody
 • Ephrin B1-B2-B3 (EFNB1) Antibody
 • 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) Recombinant Protein
 • Myoglobin (MB) Antibody
 • HLA Class 1 Antigen B8 (HLA-B) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ALDH1A3 antibody :: Rabbit anti-Human, mouse ALDH1A3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9213574
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ALDH1A3, Polyclonal Antibody

★Popular Item★
 Also Known As   

ALDH1A3 Antibody (N-term)

 Product Synonym Names    Aldehyde dehydrogenase family 1 member A3; Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; ALDH1A3; ALDH6
 Product Gene Name   

anti-ALDH1A3 antibody

[Similar Products]
 Antibody/Peptide Pairs    ALDH1A3 peptide (MBS9227313) is used for blocking the activity of ALDH1A3 antibody (MBS9213574)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence Positions    24-51
 OMIM    600463
 3D Structure    ModBase 3D Structure for P47895
Section Bar
 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human, mouse
Section Bar
 Specificity    This ALDH1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human ALDH1A3.
 Purity/Purification    Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
 Concentration    Vial Concentration: 2 (lot specific)
Section Bar
 Antigen Type    Synthetic Peptide
 Crown Antibody    Yes
 Antigen Source    HUMAN
 Function    Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity).
 Cellular Location    Cytoplasm
 Tissue Location    Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Section Bar
 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-ALDH1A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-ALDH1A3 antibody

   Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme ALDH1A3 uses retinal as a substrate, either in a free or cellular retinol-binding protein form.
 Product Categories/Family for anti-ALDH1A3 antibody    Crown Antibodies; Metabolism; Neuroscience; Signal Transduction
 Applications Tested/Suitable for anti-ALDH1A3 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-ALDH1A3 antibody    WB~~1:1000
IHC-P~~1:10~50
Section Bar
 Western Blot (WB) of anti-ALDH1A3 antibody    ALDH1A3 Antibody (N-term) western blot analysis in 293,Y79 cell line lysates (35ug/lane).This demonstrates the ALDH1A3 antibody detected the ALDH1A3 protein (arrow).
anti-ALDH1A3 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-ALDH1A3 antibody    Formalin-fixed and paraffin-embedded human kideny tissue reacted with ALDH1A3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
anti-ALDH1A3 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ALDH1A3. It may not necessarily be applicable to this product.
 NCBI GI #    153266822
 NCBI GeneID    220
 NCBI Accession #    NP_000684.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000693.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P47895 [Other Products]
 UniProt Secondary Accession #    Q6NT64 [Other Products]
 UniProt Related Accession #    P47895 [Other Products]
 Molecular Weight    56108
Table BarTOPTable Bar
 NCBI Official Full Name    aldehyde dehydrogenase family 1 member A3 isoform 1
 NCBI Official Synonym Full Names    aldehyde dehydrogenase 1 family, member A3
 NCBI Official Symbol    ALDH1A3 [Similar Products]
 NCBI Official Synonym Symbols   
ALDH6; MCOP8; RALDH3; ALDH1A6
[Similar Products]
 NCBI Protein Information    aldehyde dehydrogenase family 1 member A3
 UniProt Protein Name    Aldehyde dehydrogenase family 1 member A3
 UniProt Synonym Protein Names   
Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3
 Protein Family    Aldehyde dehydrogenase family
 UniProt Gene Name    ALDH1A3 [Similar Products]
 UniProt Synonym Gene Names    ALDH6; RALDH-3; RalDH3 [Similar Products]
 UniProt Entry Name    AL1A3_HUMAN
Section Bar
 NCBI Summary for ALDH1A3    This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Section Bar
 UniProt Comments for ALDH1A3    ALDH1A3: Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system. Belongs to the aldehyde dehydrogenase family.

Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - histidine; EC 1.2.1.5; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tyrosine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase

Chromosomal Location of Human Ortholog: 15q26.3

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; protein homodimerization activity; aldehyde dehydrogenase [NAD(P)+] activity; retinal dehydrogenase activity

Biological Process: inner ear morphogenesis; retinal metabolic process; embryonic eye morphogenesis; righting reflex; retinol metabolic process; positive regulation of apoptosis; olfactory pit development; optic cup morphogenesis involved in camera-type eye development; retinoic acid metabolic process; locomotory behavior; neuromuscular process controlling balance; nucleus accumbens development

Disease: Microphthalmia, Isolated 8
Table BarTOPTable Bar
 

Product References and Citations for anti-ALDH1A3 antibody

   Rexer,B.N., Cancer Res. 61 (19), 7065-7070 (2001)
Yoshida,A., Eur. J. Biochem. 251 (3), 549-557 (1998)
Section Bar
 Research Articles on ALDH1A3    1. Mutations in ALDH1A3 represent a frequent cause of microphthalmia/anophthalmia in consanguineous families.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-ALDH1A3 antibodyDiseases associated with anti-ALDH1A3 antibody
 Products by Pathway  Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 D-galactarate Degradation I Pathway antibodies  D-galactarate Degradation I Pathway Diagram
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >6 publications with ALDH1A3 and Adenocarcinoma
 Lung Neoplasms Antibodies  >4 publications with ALDH1A3 and Lung Neoplasms
 Lung Diseases Antibodies  >4 publications with ALDH1A3 and Lung Diseases
 Breast Neoplasms Antibodies  >4 publications with ALDH1A3 and Breast Neoplasms
 Respiratory Tract Diseases Antibodies  >4 publications with ALDH1A3 and Respiratory Tract Diseases
 Carcinoma, Squamous Cell Antibodies  >3 publications with ALDH1A3 and Carcinoma, Squamous Cell
 Disease Models, Animal Antibodies  >3 publications with ALDH1A3 and Disease Models, Animal
 Pancreatic Neoplasms Antibodies  >3 publications with ALDH1A3 and Pancreatic Neoplasms
 Inflammation Antibodies  >3 publications with ALDH1A3 and Inflammation
 Infertility, Female Antibodies  >2 publications with ALDH1A3 and Infertility, Female
Organs/Tissues associated with anti-ALDH1A3 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >17 publications with ALDH1A3 and Eye
 Lung Antibodies  >10 publications with ALDH1A3 and Lung
 Liver Antibodies  >7 publications with ALDH1A3 and Liver
 Skin Antibodies  >7 publications with ALDH1A3 and Skin
 Brain Antibodies  >7 publications with ALDH1A3 and Brain
 Embryonic Tissue Antibodies  >4 publications with ALDH1A3 and Embryonic Tissue
 Thyroid Antibodies  >4 publications with ALDH1A3 and Thyroid
 Prostate Antibodies  >4 publications with ALDH1A3 and Prostate
 Mammary Gland Antibodies  >3 publications with ALDH1A3 and Mammary Gland
 Adipose Tissue Antibodies  >3 publications with ALDH1A3 and Adipose Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions