NP_001292171.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,151 Da
NCBI Official Full Name
UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform 2
NCBI Official Synonym Full Names
ALG14, UDP-N-acetylglucosaminyltransferase subunit
NCBI Official Synonym Symbols
NCBI Protein Information
UDP-N-acetylglucosamine transferase subunit ALG14 homolog
UniProt Protein Name
UDP-N-acetylglucosamine transferase subunit ALG14 homolog
UniProt Entry Name
ALG14_HUMAN
NCBI Summary for ALG14
This gene is a member of the glycosyltransferase 1 family. The encoded protein and ALG13 are thought to be subunits of UDP-GlcNAc transferase, which catalyzes the first two committed steps in endoplasmic reticulum N-linked glycosylation. Mutations in this gene have been linked to congenital myasthenic syndrome (CMSWTA). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
UniProt Comments for ALG14
ALG14: May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER. Belongs to the ALG14 family.
Protein type: Membrane protein, integral; Glycan Metabolism - N-glycan biosynthesis
Chromosomal Location of Human Ortholog: 1p21.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane; nuclear membrane
Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine
Disease: Myasthenic Syndrome, Congenital, Without Tubular Aggregates
Research Articles on ALG14
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Products associated with anti-ALG14 antibody
Pathways associated with anti-ALG14 antibody
Diseases associated with anti-ALG14 antibody
Organs/Tissues associated with anti-ALG14 antibody
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