Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ALKBH1 rightarrow Polyclonal ALKBH1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Calcium-dependent phospholipase A2 (PLA2G5) Antibody
 • Fibromodulin (FMOD) ELISA Kit
 • QDPR Antibody
 • Myeloid Lineage Antibody
 • PHD2 (LOC100170695) Antibody
 • DLGAP1 Antibody
 • UV excision repair protein RAD23 homolog A (RAD23A) Recombinant Protein
 • IgG IgM (IgG-IgM) Antibody
 • 1-acyl-sn-glycerol-3-phosph ate acyltransferase alpha (AGPAT1... ELISA Kit
 • CTNS siRNA
 • Taste receptor type 2 member 46 (TAS2R46) Recombinant Protein
 • Iohexol Chemical Reference
 • Npc1 Antibody
 • Lactate Dehydrogenase, pan (Ldha) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ALKBH1 antibody :: Rabbit anti-Human ALKBH1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS536459
Western Blot (WB)
Unit / Price
0.05 mg  /  $455 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ALKBH1, Polyclonal Antibody

 Also Known As   

ALKBH1 antibody

 Product Synonym Names    Polyclonal ALKBH1; Anti-ALKBH1; ALKBH 1; alkB; E Coli; ALKBH1; ALKBH-1; ALKBH; alkylation repair homolog 1; ABH; hABH; ABH1
 Product Gene Name   

anti-ALKBH1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    605345
 3D Structure    ModBase 3D Structure for Q13686
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Form/Format    Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
 Concentration    1 mg/ml (lot specific)
Section Bar
 Biological Significance    This gene encodes a homolog to the E Coli alkB gene product. The E Coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
 Immunogen    ALKBH1 antibody was raised in rabbit using the N terminal of ALKBH1 as the immunogen
Section Bar
 Preparation and Storage    Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-ALKBH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-ALKBH1 antibody

   Affinity purified rabbit polyclonal ALKBH1 antibody
 Product Categories/Family for anti-ALKBH1 antibody    Infectious Disease; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-ALKBH1 antibody   

Western Blot (WB)

 Application Notes for anti-ALKBH1 antibody    Optimal conditions to be determined by the end user
Section Bar
 Western Blot (WB) of anti-ALKBH1 antibody    Western Blot showing ALKBH1 antibody used at a concentration of 1 ug/ml against Fetal Kidney Lysate
anti-ALKBH1 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ALKBH1. It may not necessarily be applicable to this product.
 NCBI GI #    87298840
 NCBI GeneID    8846
 NCBI Accession #    NP_006011.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006020.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q13686 [Other Products]
 UniProt Secondary Accession #    Q8TAU1; Q9ULA7 [Other Products]
 UniProt Related Accession #    Q13686 [Other Products]
 Molecular Weight    43,832 Da
Table BarTOPTable Bar
 NCBI Official Full Name    alkylated DNA repair protein alkB homolog 1
 NCBI Official Synonym Full Names    alkB homolog 1, histone H2A dioxygenase
 NCBI Official Symbol    ALKBH1 [Similar Products]
 NCBI Official Synonym Symbols   
ABH; ABH1; alkB; hABH; ALKBH
[Similar Products]
 NCBI Protein Information    alkylated DNA repair protein alkB homolog 1
 UniProt Protein Name    Alkylated DNA repair protein alkB homolog 1
 UniProt Synonym Protein Names   
Alpha-ketoglutarate-dependent dioxygenase ABH1; DNA lyase ABH1 (EC:4.2.99.18); DNA oxidative demethylase ALKBH1
 Protein Family    DNA demethylase
 UniProt Gene Name    ALKBH1 [Similar Products]
 UniProt Synonym Gene Names    ABH; ABH1; ALKBH [Similar Products]
 UniProt Entry Name    ALKB1_HUMAN
Section Bar
 NCBI Summary for ALKBH1    This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for ALKBH1    ALKBH: Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron. Belongs to the alkB family.

Protein type: EC 4.2.99.18; EC 1.14.11.33; DNA repair, damage

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrion

Molecular Function: DNA-(apurinic or apyrimidinic site) lyase activity; ferrous iron binding; chemoattractant activity

Biological Process: developmental growth; DNA dealkylation; positive chemotaxis; in utero embryonic development; RNA repair; neuron migration; negative regulation of neuron apoptosis; DNA repair; DNA catabolic process, endonucleolytic; neurite development; placenta development
Table BarTOPTable Bar
 Research Articles on ALKBH1    1. ALKBH1's role in class switch recombination and abasic site cleavage during base excision repair
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ALKBH1 antibodyPathways associated with anti-ALKBH1 antibody
 Reference Product  PubMed Publications
 ALKBH3 antibody  >6 publications with ALKBH1 and ALKBH3
 ALKBH2 antibody  >4 publications with ALKBH1 and ALKBH2
 ALKBH8 antibody  >4 publications with ALKBH1 and ALKBH8
 ALKBH7 antibody  >2 publications with ALKBH1 and ALKBH7
 ALKBH4 antibody  >1 publications with ALKBH1 and ALKBH4
 Products by Pathway  Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
Diseases associated with anti-ALKBH1 antibodyOrgans/Tissues associated with anti-ALKBH1 antibody
 Disease Name  Pubmed Publications
 Craniofacial Abnormalities Antibodies  >1 publications with ALKBH1 and Craniofacial Abnormalities
 Neoplasms, Experimental Antibodies  >1 publications with ALKBH1 and Neoplasms, Experimental
 Inflammation Antibodies  >1 publications with ALKBH1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >3 publications with ALKBH1 and Testis
 Lung Antibodies  >3 publications with ALKBH1 and Lung
 Bone Antibodies  >2 publications with ALKBH1 and Bone
 Placenta Antibodies  >1 publications with ALKBH1 and Placenta
 Eye Antibodies  >1 publications with ALKBH1 and Eye
 Blood Antibodies  >1 publications with ALKBH1 and Blood
 Connective Tissue Antibodies  >1 publications with ALKBH1 and Connective Tissue
 Skin Antibodies  >1 publications with ALKBH1 and Skin
 Embryonic Tissue Antibodies  >1 publications with ALKBH1 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions