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anti-ALX3 antibody :: Rabbit ALX3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS834255
Western Blot
Unit / Price
0.1 mg  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ALX3, Polyclonal Antibody

 Also Known As   

ALX3 antibody

 Product Synonym Names    Polyclonal ALX3; Anti-ALX3; ALX 3; ALX-3; ALX3
 Product Gene Name   

anti-ALX3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for O70137
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mouse, Rat, Human
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 Form/Format    Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
 Concentration    1 mg/ml (lot specific)
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 Biological Significance    Mouse Alx3 is a homeobox gene that is related to the Drosophila aristaless gene and to a group of vertebrate genes including Prx1, Prx2, Cart1, and Alx4. The protein encoded contains a diverged variant of a conserved peptide sequence present near the carboxyl terminus of at least 15 different paired-class-homeodomain proteins. Alx3 is expressed in mouse embryos from 8 days of gestation onward in a characteristic pattern, predominantly in neural crest-derived mesenchyme and in lateral plate mesoderm.
 Immunogen    ALX3 antibody was raised in rabbit using the N terminal of ALX3 as the immunogen
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 Preparation and Storage    Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-ALX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ALX3 antibody

   Rabbit polyclonal ALX3 antibody
 Product Categories/Family for anti-ALX3 antibody    Differentiation & Development
 Applications Tested/Suitable for anti-ALX3 antibody   

Western Blot (WB)

 Application Notes for anti-ALX3 antibody    WB: 2.5 ug/ml
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 Western Blot of anti-ALX3 antibody    Western Blot analysis using ALX3 antibody
ALX3 antibody used at 0.2-1 ug/ml to detect target protein.
anti-ALX3 antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for ALX3. It may not necessarily be applicable to this product.
 NCBI GI #    7106250
 NCBI GeneID    11694
 NCBI Accession #    NP_031467 [Other Products]
 NCBI GenBank Nucleotide #    NM_007441.3 [Other Products]
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 UniProt Primary Accession #    O70137 [Other Products]
 UniProt Related Accession #    O70137 [Other Products]
 Molecular Weight    36,851 Da
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 NCBI Official Full Name    homeobox protein aristaless-like 3
 NCBI Official Synonym Full Names    aristaless-like homeobox 3
 NCBI Official Symbol    Alx3 [Similar Products]
 NCBI Protein Information    homeobox protein aristaless-like 3
 UniProt Protein Name    Homeobox protein aristaless-like 3
 UniProt Synonym Protein Names   
Proline-rich transcription factor ALX3
 Protein Family    Homeobox protein
 UniProt Gene Name    Alx3 [Similar Products]
 UniProt Entry Name    ALX3_MOUSE
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 NCBI Summary for ALX3    This gene belongs to Group 1 of aristaless-like genes, which are characterized by the presence of an aristaless domain and a conserved paired-like homeodomain. The encoded protein acts as a transcriptional regulator. The protein plays a role in the development of craniofacial and appendicular skeleton and may have a role in pancreatic function. [provided by RefSeq, Apr 2013]
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 UniProt Comments for ALX3    ALX3: Transcriptional regulator with a possible role in patterning of mesoderm during development. Defects in ALX3 are the cause of frontonasal dysplasia type 1 (FND1); also called frontonasal malformation (FNM) or frontorhiny. The term frontonasal dysplasia describes an array of abnormalities affecting the eyes, forehead and nose and linked to midfacial dysraphia. The clinical picture is highly variable. Major findings include true ocular hypertelorism; broadening of the nasal root; median facial cleft affecting the nose and/or upper lip and palate; unilateral or bilateral clefting of the alae nasi; lack of formation of the nasal tip; anterior cranium bifidum occultum; a V-shaped or widow's peak frontal hairline. Belongs to the paired homeobox family.

Protein type: Transcription, coactivator/corepressor; DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: embryonic forelimb morphogenesis; regulation of apoptosis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; embryonic hindlimb morphogenesis; pattern specification process; embryonic skeletal morphogenesis
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 Research Articles on ALX3    1. Pdx1, USF1 and USF2 co-ordinately regulate Alx3 gene expression in pancreatic beta-cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ALX3 antibodyDiseases associated with anti-ALX3 antibody
 Reference Product  PubMed Publications
 Tbx15 antibody  >2 publications with ALX3 and Tbx15
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >14 publications with ALX3 and Congenital Abnormalities
 Diabetes Mellitus Antibodies  >2 publications with ALX3 and Diabetes Mellitus
 FRONTONASAL DYSPLASIA 1 Antibodies  >2 publications with ALX3 and FRONTONASAL DYSPLASIA 1
 Heart Defects, Congenital Antibodies  >1 publications with ALX3 and Heart Defects, Congenital
 Maxillofacial Abnormalities Antibodies  >1 publications with ALX3 and Maxillofacial Abnormalities
 Disease Models, Animal Antibodies  >1 publications with ALX3 and Disease Models, Animal
Organs/Tissues associated with anti-ALX3 antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >6 publications with ALX3 and Embryonic Tissue
 Eye Antibodies  >2 publications with ALX3 and Eye
 Brain Antibodies  >2 publications with ALX3 and Brain
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