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anti-AMBP antibody :: Rabbit anti-Human AMBP Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9210145
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AMBP, Polyclonal Antibody

★Popular Item★
 Also Known As   

AMBP Antibody (N-term)

 Product Synonym Names    Protein AMBP; Alpha-1-microglobulin; Protein HC; Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge; Inter-alpha-trypsin inhibitor light chain; ITI-LC; Bikunin; EDC1; HI-30; Uronic-acid-rich protein; Trypstatin; AMBP; HCP; ITIL
 Product Gene Name   

anti-AMBP antibody

[Similar Products]
 Antibody/Peptide Pairs    AMBP peptide (MBS9220175) is used for blocking the activity of AMBP antibody (MBS9210145)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    77-104
 OMIM    176870
 3D Structure    ModBase 3D Structure for P02760
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 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This AMBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-104 amino acids from the N-terminal region of human AMBP.
 Purity/Purification    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
 Concentration    Vial Concentration: 0.33 (lot specific)
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 Antigen Type    Synthetic Peptide
 Antigen Source    HUMAN
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-AMBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-AMBP antibody

   This gene encodes a complex glycoprotein secreted in
plasma. The precursor is proteolytically processed into distinct
functioning proteins: alpha-1-microglobulin, which belongs to the
superfamily of lipocalin transport proteins and may play a role in
the regulation of inflammatory processes, and bikunin, which is a
urinary trypsin inhibitor belonging to the superfamily of
Kunitz-type protease inhibitors and plays an important role in many
physiological and pathological processes. This gene is located on
chromosome 9 in a cluster of lipocalin genes.
 Product Categories/Family for anti-AMBP antibody    Cancer; Cardiovascular; Cell Biology; Immunology; Metabolism
 Applications Tested/Suitable for anti-AMBP antibody   

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-AMBP antibody    WB~~1:1000
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 Western Blot (WB) of anti-AMBP antibody    AMBP Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the AMBP antibody detected the AMBP protein (arrow).
anti-AMBP antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-AMBP antibody    AMBP Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AMBP Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-AMBP antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for AMBP. It may not necessarily be applicable to this product.
 NCBI GI #    4502067
 NCBI GeneID    259
 NCBI Accession #    NP_001624.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001633.3 [Other Products]
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 UniProt Primary Accession #    P02760 [Other Products]
 UniProt Secondary Accession #    P00977; P02759; P78491; Q2TU33; Q5TBD7; Q9UC58; Q9UDI8 [Other Products]
 UniProt Related Accession #    P02760 [Other Products]
 Molecular Weight    38999
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 NCBI Official Full Name    protein AMBP preproprotein
 NCBI Official Synonym Full Names    alpha-1-microglobulin/bikunin precursor
 NCBI Official Symbol    AMBP [Similar Products]
 NCBI Official Synonym Symbols   
A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
[Similar Products]
 NCBI Protein Information    protein AMBP
 UniProt Protein Name    Protein AMBP
 UniProt Synonym Protein Names   
Alpha-1-microglobulin; Protein HC
 Protein Family    Protein
 UniProt Gene Name    AMBP [Similar Products]
 UniProt Synonym Gene Names    HCP; ITIL; Protein HC; ITI-LC [Similar Products]
 UniProt Entry Name    AMBP_HUMAN
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 NCBI Summary for AMBP    This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AMBP    AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q32-q33

Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; extracellular region; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; IgA binding; heme binding; calcium oxalate binding; calcium channel inhibitor activity

Biological Process: negative regulation of JNK cascade; receptor-mediated endocytosis; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage
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Product References and Citations for anti-AMBP antibody

   Olsson, M.G., et al. Radiat. Res. 174(5):590-600(2010)
Allhorn, M., et al. Blood 99(6):1894-1901(2002)
Amoresano, A., et al. Eur. J. Biochem. 267(7):2105-2112(2000)
Xu, Y., et al. J. Mol. Biol. 276(5):955-966(1998)
Vetr, H., et al. Biol. Chem. Hoppe-Seyler 371(12):1185-1196(1990)
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 Research Articles on AMBP    1. placental alpha microglobulin-1 is a sensitive and specific test to assess rupture of membranes in patients with an equivocal diagnosis based on simple tests
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AMBP antibodyDiseases associated with anti-AMBP antibody
 Reference Product  PubMed Publications
 ALB antibody  >2 publications with AMBP and ALB
 SERPINC1 antibody  >2 publications with AMBP and SERPINC1
 SERPINA1 antibody  >1 publications with AMBP and SERPINA1
 ITIH1 antibody  >1 publications with AMBP and ITIH1
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >62 publications with AMBP and Cardiovascular Diseases
 Hypertension Antibodies  >45 publications with AMBP and Hypertension
 Inflammation Antibodies  >23 publications with AMBP and Inflammation
 Necrosis Antibodies  >16 publications with AMBP and Necrosis
 Kidney Diseases Antibodies  >12 publications with AMBP and Kidney Diseases
 Heart Diseases Antibodies  >12 publications with AMBP and Heart Diseases
 Hemorrhage Antibodies  >9 publications with AMBP and Hemorrhage
 Liver Diseases Antibodies  >7 publications with AMBP and Liver Diseases
 Drug-Induced Liver Injury Antibodies  >6 publications with AMBP and Drug-Induced Liver Injury
 Disease Models, Animal Antibodies  >5 publications with AMBP and Disease Models, Animal
Organs/Tissues associated with anti-AMBP antibody
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >36 publications with AMBP and Heart
 Liver Antibodies  >29 publications with AMBP and Liver
 Kidney Antibodies  >22 publications with AMBP and Kidney
 Intestine Antibodies  >14 publications with AMBP and Intestine
 Brain Antibodies  >13 publications with AMBP and Brain
 Muscle Antibodies  >8 publications with AMBP and Muscle
 Lung Antibodies  >5 publications with AMBP and Lung
 Pancreas Antibodies  >3 publications with AMBP and Pancreas
 Embryonic Tissue Antibodies  >2 publications with AMBP and Embryonic Tissue
 Spleen Antibodies  >1 publications with AMBP and Spleen
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