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anti-ANKLE1 antibody :: Chicken ANKLE1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150337
Western Blot (WB)
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ANKLE1, Polyclonal Antibody

 Also Known As   

ANKLE1 Antibody

 Product Synonym Names    ANKLE1; LEM3; LEMD6; ANKRD41; LEM3; Ankyrin repeat and LEM domain-containing protein 1; Ankyrin repeat domain-containing protein 41; ankyrin repeat and LEM domain containing 1
 Product Gene Name   

anti-ANKLE1 antibody

[Similar Products]
 Antibody/Peptide Pairs    ANKLE1 peptide (MBS152528) is used for blocking the activity of ANKLE1 antibody (MBS150337)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q8NAG6
 Clonality    Polyclonal
 Isotype    IgY
 Host    Chicken
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2
 Purity/Purification    ANKLE1 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    ANKLE1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1.
 Buffer    ANKLE1 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    ANKLE1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-ANKLE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ANKLE1 antibody

   ANKLE1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.
 Applications Tested/Suitable for anti-ANKLE1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-ANKLE1 antibody    ANKLE1 antibody can be used for detection of ANKLE1 by Western blot at 1 - 2 mug/mL.
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 Western Blot (WB) of anti-ANKLE1 antibody    Western blot analysis of ANKLE1 in 293 cell lysate with ANKLE1 antibody at (A) 1 and (B) 2 μg/mL.
anti-ANKLE1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ANKLE1. It may not necessarily be applicable to this product.
 NCBI GI #    168229256
 NCBI GeneID    126549
 NCBI Accession #    NP_689576 [Other Products]
 NCBI GenBank Nucleotide #    NM_152363.4 [Other Products]
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 UniProt Primary Accession #    Q8NAG6 [Other Products]
 UniProt Secondary Accession #    Q8N8J8; A8VU82 [Other Products]
 UniProt Related Accession #    Q8NAG6 [Other Products]
 Molecular Weight    62,255 Da
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 NCBI Official Full Name    ankyrin repeat and LEM domain-containing protein 1
 NCBI Official Synonym Full Names    ankyrin repeat and LEM domain containing 1
 NCBI Official Symbol    ANKLE1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    ankyrin repeat and LEM domain-containing protein 1; LEM domain containing 6; LEM-domain containing 3; ankyrin repeat domain-containing protein 41
 UniProt Protein Name    Ankyrin repeat and LEM domain-containing protein 1
 UniProt Synonym Protein Names   
Ankyrin repeat domain-containing protein 41; LEM-domain containing protein 3
 Protein Family    Ankyrin repeat and LEM domain-containing protein
 UniProt Gene Name    ANKLE1 [Similar Products]
 UniProt Synonym Gene Names    ANKRD41; LEM3 [Similar Products]
 UniProt Entry Name    ANKL1_HUMAN
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 UniProt Comments for ANKLE1    ANKRD41: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13.11
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 Research Articles on ANKLE1    1. Ankle1 is conserved in metazoans and contains a unique C-terminal GIY-YIG motif that confers endonuclease activity in vitro and in vivo
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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