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anti-APIP antibody :: Rabbit APAF1 interacting protein Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713450 anti-APIP antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

APAF1 interacting protein (APIP), Polyclonal Antibody

 Also Known As   

Rabbit anti-human APAF1 interacting protein polyclonal Antibody

 Product Synonym Names    APAF1 interacting protein; APIP; APIP2; CGI-29; CGI29; MMRP19; dJ179L10.2
 Product Gene Name   

anti-APIP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612491
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human APIP
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66318 / sc-66319 / sc-292256
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-APIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-APIP antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for APIP. It may not necessarily be applicable to this product.
 NCBI GI #    119588567
 NCBI GeneID    51074
 NCBI Accession #    EAW68161.1 [Other Products]
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 UniProt Secondary Accession #    Q6PJX6; Q8WVU2; Q96HK2; Q9Y318; A8K9D3 [Other Products]
 UniProt Related Accession #    Q96GX9 [Other Products]
 Molecular Weight    22,858 Da [Similar Products]
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 NCBI Official Full Name    APAF1 interacting protein
 NCBI Official Synonym Full Names    APAF1 interacting protein
 NCBI Official Symbol    APIP [Similar Products]
 NCBI Official Synonym Symbols   
APIP2; CGI29; hAPIP; CGI-29; MMRP19
[Similar Products]
 NCBI Protein Information    methylthioribulose-1-phosphate dehydratase; APIP; MTRu-1-P dehydratase; APAF1-interacting protein; probable methylthioribulose-1-phosphate dehydratase
 UniProt Protein Name    Methylthioribulose-1-phosphate dehydratase
 UniProt Synonym Protein Names   
APAF1-interacting protein
 UniProt Gene Name    APIP [Similar Products]
 UniProt Synonym Gene Names    MTRu-1-P dehydratase [Similar Products]
 UniProt Entry Name    MTNB_HUMAN
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 NCBI Summary for APIP    APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008]
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 UniProt Comments for APIP    MMRP19: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c- dependent and APAF1-mediated cell death. Belongs to the aldolase class II family. MtnB subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - cysteine and methionine; EC 4.2.1.109; Apoptosis

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm

Molecular Function: identical protein binding; 5-methylthioribulose-1-phosphate 4-dehydratase activity; protein binding; zinc ion binding

Biological Process: methionine salvage; apoptosis; sulfur amino acid metabolic process; methionine biosynthetic process from S-adenosylmethionine; negative regulation of apoptosis; polyamine metabolic process
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 Research Articles on APIP    1. APIP/MtnB functions as a cell death inhibitor independently of its MtnB enzyme activity for apoptosis induced by either hypoxia or etoposide, but dependently for caspase-1-induced pyroptosis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Rabbit anti-human APAF1 interacting protein polyclonal Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS9328289  Bovine Probable methylthioribulose-1-phosphate dehydratase, APIP ELISA Kit  MBS713450  Rabbit anti-human APAF1 interacting protein polyclonal Antibody
 MBS9331125  Mouse Probable methylthioribulose-1-phosphate dehydratase, APIP ELISA Kit  MBS145010  Recombinant Human APAF1 interacting protein
 MBS9339712  Chicken Probable methylthioribulose-1-phosphate dehydratase, APIP ELISA Kit
Products associated with anti-APIP antibodyPathways associated with anti-APIP antibody
 Reference Product  PubMed Publications
 CASP9 antibody  >7 publications with APIP and CASP9
 APAF1 antibody  >5 publications with APIP and APAF1
 Products by Pathway  Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 S-methyl-5-thio-alpha-D-ribose 1-phosphate Degradation Pathway antibodies  S-methyl-5-thio-alpha-D-ribose 1-phosphate Degradation Pathway Diagram
Diseases associated with anti-APIP antibodyOrgans/Tissues associated with anti-APIP antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with APIP and Inflammation
 Liver Diseases Antibodies  >1 publications with APIP and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with APIP and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with APIP and Lung
 Bone Antibodies  >1 publications with APIP and Bone
 Heart Antibodies  >1 publications with APIP and Heart
 Thymus Antibodies  >1 publications with APIP and Thymus
 Prostate Antibodies  >1 publications with APIP and Prostate
 Liver Antibodies  >1 publications with APIP and Liver
 Muscle Antibodies  >1 publications with APIP and Muscle
 Kidney Antibodies  >1 publications with APIP and Kidney
 Bone Marrow Antibodies  >1 publications with APIP and Bone Marrow
 Brain Antibodies  >1 publications with APIP and Brain
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