Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow APBA1 rightarrow Polyclonal APBA1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CD62P ELISA Kit
 • S-adenosylmethionine:tRNA ribosyltransferase-isomeras e (queA... Recombinant Protein
 • SLC22A5 Antibody
 • CHCHD3 Antibody
 • Estriol HRP Conjugate
 • Trafficking Protein Particle Complex 2 (TRAPPC2) Recombinant Protein
 • OR52E4 Antibody
 • leucine rich repeat and Ig domain containing 4 (LINGO4) ELISA Kit
 • Angiotensin 1 (ANG1) ELISA Kit
 • Pahyroid Hormone Related Protein (PTHrP) ELISA Kit
 • Growth Hormone (rHuGH) (GH1) Recombinant Protein
 • 5-HYDROXY-BENDAZAC Antibody
 • NPFF2 - NPFFR2 Antibody
 • Elastase 3B (ELA3B) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-APBA1 antibody :: Goat APBA1/MINT1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420485
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

APBA1/MINT1, Polyclonal Antibody

 Also Known As   

Goat anti-APBA1/MINT1 Antibody

 Product Synonym Names    APBA1; MINT1; amyloid beta (A4) precursor protein-binding, family A, member 1 (X11); D9S411E; mint; X11; X11A; X11ALPHA; adaptor protein X11alpha amyloid beta A4 precursor protein-binding, family A, member 1; neuron-specific X11 protein; neuronal munc1; APBA1 antibody; MINT1 antibody; amyloid beta (A4) precursor protein-binding; family A; member 1 (X11) antibody; D9S411E antibody; mint antibody; X11 antibody; X11A antibody; X11ALPHA antibody; adaptor protein X11alpha amyloid beta A4 precursor protein-binding; family A; member 1 antibody; neuron-specific X11 protein antibody; neuronal munc18-1-interacting protein 1 antibody; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein antibody; APBA1 / MINT1
 Product Gene Name   

anti-APBA1 antibody

[Similar Products]
 Product Synonym Gene Name    MINT1 [Similar Products]
 Antibody/Peptide Pairs    APBA1 / MINT1 peptide (MBS426739) is used for blocking the activity of APBA1/MINT1 antibody (MBS420485)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence    EASHPSQDGK RQYK
 OMIM    602414
Section Bar
 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
Section Bar
 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
Section Bar
 Immunogen    Peptide with sequence C-EASHPSQDGKRQYK, from the internal region of the protein sequence according to NP_001154.2.
 Epitope    Internal region
Section Bar
 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-APBA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-APBA1 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-APBA1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 100kDa band observed in Human Brain (Cerebellum and Hippocampus) lysates (calculated MW of 92.9kDa according to NP_001154.2). Recommended concentration: 0.1-0.3ug/ml.
Section Bar
 Western Blot (WB) of anti-APBA1 antibody    (0.1ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-APBA1 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for APBA1. It may not necessarily be applicable to this product.
 NCBI GI #    22035548
 NCBI GeneID    320
 NCBI Accession #    NP_001154.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001163.3 [Other Products]
Section Bar
 UniProt Secondary Accession #    O14914; O60570; Q5VYR8 [Other Products]
 UniProt Related Accession #    Q02410 [Other Products]
 Molecular Weight    91,594 Da
Table BarTOPTable Bar
 NCBI Official Full Name    amyloid beta A4 protein-binding family A member 1
 NCBI Official Synonym Full Names    amyloid beta precursor protein binding family A member 1
 NCBI Official Symbol    APBA1 [Similar Products]
 NCBI Official Synonym Symbols   
X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA
[Similar Products]
 NCBI Protein Information    amyloid beta A4 precursor protein-binding family A member 1
 UniProt Protein Name    Amyloid beta A4 precursor protein-binding family A member 1
 UniProt Synonym Protein Names   
Adapter protein X11alpha; Neuron-specific X11 protein; Neuronal Munc18-1-interacting protein 1; Mint-1
 Protein Family    Amyloid beta A4 precursor protein-binding family
 UniProt Gene Name    APBA1 [Similar Products]
 UniProt Synonym Gene Names    MINT1; X11; Mint-1 [Similar Products]
 UniProt Entry Name    APBA1_HUMAN
Section Bar
 NCBI Summary for APBA1    The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for APBA1    APBA1: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9q21.12

Cellular Component: cytosol

Molecular Function: protein binding

Biological Process: axon cargo transport; cell adhesion; nervous system development; neurotransmitter secretion; synaptic transmission
Table BarTOPTable Bar
 Research Articles on APBA1    1. Mints are necessary for activity-induced APP and PS1 trafficking and provide insight into the cellular fate of APP in endocytic pathways essential for Abeta production.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-APBA1 antibodyPathways associated with anti-APBA1 antibody
 Reference Product  PubMed Publications
 APP antibody  >39 publications with APBA1 and APP
 CASK antibody  >15 publications with APBA1 and CASK
 KIF17 antibody  >6 publications with APBA1 and KIF17
 CASKIN1 antibody  >4 publications with APBA1 and CASKIN1
 APLP2 antibody  >4 publications with APBA1 and APLP2
 STXBP1 antibody  >3 publications with APBA1 and STXBP1
 APBB2 antibody  >1 publications with APBA1 and APBB2
 Products by Pathway  Pathway Diagram
 Dopamine Neurotransmitter Release Cycle Pathway antibodies  Dopamine Neurotransmitter Release Cycle Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Release Cycle Pathway antibodies  Neurotransmitter Release Cycle Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram
Diseases associated with anti-APBA1 antibodyOrgans/Tissues associated with anti-APBA1 antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >52 publications with APBA1 and Brain Diseases
 Death Antibodies  >6 publications with APBA1 and Death
 Inflammation Antibodies  >3 publications with APBA1 and Inflammation
 Memory Disorders Antibodies  >3 publications with APBA1 and Memory Disorders
 Neoplasms, Experimental Antibodies  >2 publications with APBA1 and Neoplasms, Experimental
 Cognition Disorders Antibodies  >2 publications with APBA1 and Cognition Disorders
 Hyperplasia Antibodies  >2 publications with APBA1 and Hyperplasia
 Nerve Degeneration Antibodies  >2 publications with APBA1 and Nerve Degeneration
 Abnormalities, Multiple Antibodies  >1 publications with APBA1 and Abnormalities, Multiple
 Chromosome Aberrations Antibodies  >1 publications with APBA1 and Chromosome Aberrations
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >122 publications with APBA1 and Nerve
 Brain Antibodies  >53 publications with APBA1 and Brain
 Kidney Antibodies  >6 publications with APBA1 and Kidney
 Embryonic Tissue Antibodies  >6 publications with APBA1 and Embryonic Tissue
 Pancreas Antibodies  >2 publications with APBA1 and Pancreas
 Muscle Antibodies  >2 publications with APBA1 and Muscle
 Intestine Antibodies  >2 publications with APBA1 and Intestine
 Lung Antibodies  >1 publications with APBA1 and Lung
 Testis Antibodies  >1 publications with APBA1 and Testis
 Vascular Antibodies  >1 publications with APBA1 and Vascular
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions