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anti-APOA2 antibody :: Rabbit anti-Human APOA2 / Apolipoprotein A II Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS242643
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

APOA2 / Apolipoprotein A II, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit Polyclonal (IgG) to Human APOA2 / Apolipoprotein A II

 Product Synonym Names    Anti-APOA2 / Apolipoprotein A II Antibody IHC-plus; APOA2; Apo-AII; ApoAII; ApoA-II; Apolipoprotein A-II; Apolipoprotein A2; Apolipoprotein A II; Human APOA2; Apolipoprotein A II
 Product Gene Name   

anti-APOA2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    107670
 3D Structure    ModBase 3D Structure for P02652
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Specifically binds to human Apo AII.
 Purity/Purification    Affinity Purified
 Form/Format    75 mM PBS, 75 mM sodium chloride, pH 7.2, 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Human Apo AII.
 Immunogen    APOA2 / Apolipoprotein A II antibody was raised against human Apo AII.
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 Preparation and Storage    Long term: Add glycerol (40-50%) -20 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-APOA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-APOA2 antibody

   Apolipoprotein (Apo-) A-II is the second most abundant protein of the high density lipoprotein particles. The apo-A-II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre-peptide, a short N-terminal domain and a C-terminal domain composed of a variable number of lipid-binding amphipathic helices.
 Applications Tested/Suitable for anti-APOA2 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

 Application Notes for anti-APOA2 antibody    ELISA (1:5000 - 1:40000), IHC-P (5 ug/ml), WB (1:5000 - 1:40000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-APOA2 antibody    Anti-APOA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-APOA2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-APOA2 antibody    Anti-APOA2 antibody IHC of human testis, Leydig cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-APOA2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for APOA2. It may not necessarily be applicable to this product.
 NCBI GI #    4502149
 NCBI GeneID    336
 NCBI Accession #    NP_001634.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001643.1 [Other Products]
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 UniProt Primary Accession #    P02652 [Other Products]
 UniProt Secondary Accession #    B2R524 [Other Products]
 UniProt Related Accession #    P02652 [Other Products]
 Molecular Weight    11,175 Da
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 NCBI Official Full Name    apolipoprotein A-II preproprotein
 NCBI Official Synonym Full Names    apolipoprotein A-II
 NCBI Official Symbol    APOA2 [Similar Products]
 NCBI Official Synonym Symbols   
apoAII; Apo-AII; ApoA-II
[Similar Products]
 NCBI Protein Information    apolipoprotein A-II; apolipoprotein A2
 UniProt Protein Name    Apolipoprotein A-II
 UniProt Synonym Protein Names   
Apolipoprotein A2Cleaved into the following 2 chains:Proapolipoprotein A-II; ProapoA-II; Truncated apolipoprotein A-IIAlternative name(s):Apolipoprotein A-II(1-76)
 Protein Family    Apolipoprotein
 UniProt Gene Name    APOA2 [Similar Products]
 UniProt Synonym Gene Names    Apo-AII; ApoA-II; ProapoA-II [Similar Products]
 UniProt Entry Name    APOA2_HUMAN
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 NCBI Summary for APOA2    This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for APOA2    APOA2: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Belongs to the apolipoprotein A2 family.

Protein type: Endoplasmic reticulum; Secreted, signal peptide; Secreted; Lipid-binding

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: chylomicron; endoplasmic reticulum lumen; early endosome; extracellular region; cytosol

Molecular Function: lipid transporter activity; protein binding; protein homodimerization activity; lipase inhibitor activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; phospholipid binding; phosphatidylcholine binding; high-density lipoprotein binding; lipid binding; apolipoprotein receptor binding

Biological Process: positive regulation of catalytic activity; phototransduction, visible light; viral reproduction; protein folding; negative regulation of cholesterol transport; response to glucocorticoid stimulus; regulation of protein stability; diacylglycerol catabolic process; positive regulation of lipid catabolic process; cellular lipid metabolic process; negative regulation of lipase activity; regulation of cholesterol absorption; phospholipid efflux; negative regulation of lipid catabolic process; response to glucose stimulus; retinoid metabolic process; response to drug; cholesterol metabolic process; organ regeneration; protein amino acid oxidation; phospholipid catabolic process; positive regulation of interleukin-8 biosynthetic process; cholesterol efflux; lipoprotein metabolic process; negative regulation of cytokine secretion during immune response; cholesterol homeostasis; triacylglycerol metabolic process; reverse cholesterol transport; response to estrogen stimulus; peptidyl-methionine modification; phosphatidylcholine biosynthetic process; acute inflammatory response

Disease: Hypercholesterolemia, Familial
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 Research Articles on APOA2    1. Apolipoprotein A-II and the regulation of high density lipoproteins in cardiovascular disease. [Review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-APOA2 antibodyPathways associated with anti-APOA2 antibody
 Reference Product  PubMed Publications
 APOA1 antibody  >40 publications with APOA2 and APOA1
 APOE antibody  >17 publications with APOA2 and APOE
 APOB antibody  >17 publications with APOA2 and APOB
 APOC2 antibody  >12 publications with APOA2 and APOC2
 APOC3 antibody  >11 publications with APOA2 and APOC3
 APOA4 antibody  >5 publications with APOA2 and APOA4
 LPL antibody  >4 publications with APOA2 and LPL
 APOA5 antibody  >4 publications with APOA2 and APOA5
 APOH antibody  >3 publications with APOA2 and APOH
 Products by Pathway  Pathway Diagram
 Chylomicron-mediated Lipid Transport Pathway antibodies  Chylomicron-mediated Lipid Transport Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
Diseases associated with anti-APOA2 antibodyOrgans/Tissues associated with anti-APOA2 antibody
 Disease Name  Pubmed Publications
 Dyslipidemias Antibodies  >16 publications with APOA2 and Dyslipidemias
 Liver Diseases Antibodies  >13 publications with APOA2 and Liver Diseases
 Hyperlipidemias Antibodies  >12 publications with APOA2 and Hyperlipidemias
 Heart Diseases Antibodies  >12 publications with APOA2 and Heart Diseases
 Inflammation Antibodies  >8 publications with APOA2 and Inflammation
 Disease Models, Animal Antibodies  >7 publications with APOA2 and Disease Models, Animal
 Kidney Diseases Antibodies  >6 publications with APOA2 and Kidney Diseases
 Hepatitis Antibodies  >5 publications with APOA2 and Hepatitis
 Carcinoma, Hepatocellular Antibodies  >5 publications with APOA2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >5 publications with APOA2 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >68 publications with APOA2 and Blood
 Liver Antibodies  >25 publications with APOA2 and Liver
 Heart Antibodies  >14 publications with APOA2 and Heart
 Kidney Antibodies  >9 publications with APOA2 and Kidney
 Muscle Antibodies  >5 publications with APOA2 and Muscle
 Intestine Antibodies  >5 publications with APOA2 and Intestine
 Brain Antibodies  >3 publications with APOA2 and Brain
 Placenta Antibodies  >3 publications with APOA2 and Placenta
 Lung Antibodies  >2 publications with APOA2 and Lung
 Spleen Antibodies  >2 publications with APOA2 and Spleen
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