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anti-APOB48R antibody :: Goat APOB48R Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422145 anti-APOB48R antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

APOB48R, Polyclonal Antibody

 Also Known As   

Goat anti-APOB48R (mouse) Antibody

 Product Synonym Names    Apob48r; apolipoprotein B48 receptor; Apob-48; Apob48r antibody; apolipoprotein B48 receptor antibody; Apob-48 antibody; APOB48R (mouse)
 Product Gene Name   

anti-APOB48R antibody

[Similar Products]
 Antibody/Peptide Pairs    APOB48R peptide (MBS425070) is used for blocking the activity of APOB48R antibody (MBS422145)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    QELQARLSQP KPQ
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Mouse, Rat, Dog,
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-QELQARLSQPKPQ, from the C Terminus of the protein sequence according to NP_612183.1.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-APOB48R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-APOB48R antibody   

Peptide ELISA (EIA)

 Application Notes for anti-APOB48R antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave an approx.37kDa band in Mouse and Rat Spleen lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to NP_612183.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide.
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NCBI/Uniprot data below describe general gene information for APOB48R. It may not necessarily be applicable to this product.
 NCBI GI #    19923863
 NCBI GeneID    171504
 NCBI Accession #    NP_612183.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_138310.1 [Other Products]
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 UniProt Related Accession #    Q8VBT6 [Other Products]
 Molecular Weight    102,705 Da
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 NCBI Official Full Name    apolipoprotein B receptor
 NCBI Official Synonym Full Names    apolipoprotein B receptor
 NCBI Official Symbol    Apobr [Similar Products]
 NCBI Official Synonym Symbols   
Apob48r; Apob-48r
[Similar Products]
 NCBI Protein Information    apolipoprotein B receptor
 UniProt Protein Name    Apolipoprotein B receptor
 UniProt Synonym Protein Names   
Apolipoprotein B-100 receptor; Apolipoprotein B48 receptor; apoB-48R
 UniProt Gene Name    Apobr [Similar Products]
 UniProt Synonym Gene Names    Apob48r; Apolipoprotein B48 receptor; apoB-48R [Similar Products]
 UniProt Entry Name    APOBR_MOUSE
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 UniProt Comments for APOB48R    APOB48R: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.

Cellular Component: chylomicron; membrane; plasma membrane

Molecular Function: lipoprotein receptor activity; very-low-density lipoprotein receptor activity

Biological Process: cholesterol metabolic process; lipid metabolic process; lipid transport; steroid metabolic process; transport; triacylglycerol metabolic process
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-APOB48R antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with APOB48R and Skin
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