Q96AK3.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
NCBI Official Full Name
DNA dC->
UniProt Protein Name
DNA dC->dU-editing enzyme APOBEC-3D
UniProt Synonym Gene Names
UniProt Entry Name
ABC3D_HUMAN
UniProt Comments for APOBEC3D
APOBEC3D: Probable DNA cytidine deaminase involved in foreign DNA clearance. May provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family.
Protein type: Hydrolase; EC 3.5.4.-
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: cytoplasm
Molecular Function: zinc ion binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
Biological Process: negative regulation of retroviral genome replication; innate immune response; defense response to virus
Product References and Citations for anti-APOBEC3D antibody
Zhang, W., et al. PLoS ONE 3 (12), E3963 (2008) : Dang, Y., et al. J. Virol. 80(21):10522-10533(2006) Stenglein, M.D., et al. J. Biol. Chem. 281(25):16837-16841(2006) Conticello, S.G., et al. Mol. Biol. Evol. 22(2):367-377(2005) Harris, R.S., et al. Nat. Rev. Immunol. 4(11):868-877(2004)
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Products associated with anti-APOBEC3D antibody
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