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anti-APOLD1 antibody :: Goat APOLD1/VERGE Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422244 anti-APOLD1 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

APOLD1/VERGE, Polyclonal Antibody

 Also Known As   

Goat anti-APOLD1/VERGE Antibody

 Product Synonym Names    APOLD1; apolipoprotein L domain containing 1; DKFZP434F0318; FLJ25138; VERGE; APOLD1 antibody; apolipoprotein L domain containing 1 antibody; DKFZP434F0318 antibody; FLJ25138 antibody; VERGE antibody; APOLD1 / VERGE
 Product Gene Name   

anti-APOLD1 antibody

[Similar Products]
 Product Synonym Gene Name    VERGE [Similar Products]
 Antibody/Peptide Pairs    APOLD1 / VERGE peptide (MBS426869) is used for blocking the activity of APOLD1/VERGE antibody (MBS422244)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KSSRGHDLKI SADQ
 OMIM    612456
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-KSSRGHDLKISADQ, from the C Terminus of the protein sequence according to NP_110444.1.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-APOLD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-APOLD1 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-APOLD1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Preliminary experiments gave an approx.37kDa band in Human Brain (Frontal Cortex) lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 27.2kDa according to NP_110444.1 The 37kDa band was successfully blocked by incubation with the immunizing peptide.
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NCBI/Uniprot data below describe general gene information for APOLD1. It may not necessarily be applicable to this product.
 NCBI GI #    13540612
 NCBI GeneID    81575
 NCBI Accession #    NP_110444.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030817.1 [Other Products]
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 UniProt Secondary Accession #    Q8IVR2; Q9H0I5 [Other Products]
 UniProt Related Accession #    Q96LR9 [Other Products]
 Molecular Weight    27,063 Da
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 NCBI Official Full Name    apolipoprotein L domain containing 1
 NCBI Official Synonym Full Names    apolipoprotein L domain containing 1
 NCBI Official Symbol    APOLD1 [Similar Products]
 NCBI Official Synonym Symbols   
VERGE
[Similar Products]
 NCBI Protein Information    apolipoprotein L domain-containing protein 1
 UniProt Protein Name    Apolipoprotein L domain-containing protein 1
 UniProt Synonym Protein Names   
Vascular early response gene protein
 Protein Family    Apolipoprotein L domain-containing protein
 UniProt Gene Name    APOLD1 [Similar Products]
 UniProt Synonym Gene Names    VERGE [Similar Products]
 UniProt Entry Name    APLD1_HUMAN
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 NCBI Summary for APOLD1    APOLD1 is an endothelial cell early response protein that may play a role in regulation of endothelial cell signaling and vascular function (Regard et al., 2004 [PubMed 15102925]).[supplied by OMIM, Dec 2008]
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 UniProt Comments for APOLD1    APOLD1: May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood- brain permeability. Belongs to the apolipoprotein L family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p13.1

Cellular Component: extracellular region; integral to membrane; plasma membrane

Molecular Function: lipid binding

Biological Process: angiogenesis; cell differentiation; endothelial cell activation; lipid transport; lipoprotein metabolic process; regulation of endothelial cell differentiation; response to hypoxia
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 Research Articles on APOLD1    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-APOLD1 antibodyOrgans/Tissues associated with anti-APOLD1 antibody
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >1 publications with APOLD1 and Skin Diseases
 Hypertension Antibodies  >1 publications with APOLD1 and Hypertension
 Edema Antibodies  >1 publications with APOLD1 and Edema
 Lung Diseases Antibodies  >1 publications with APOLD1 and Lung Diseases
 Fibrosis Antibodies  >1 publications with APOLD1 and Fibrosis
 Inflammation Antibodies  >1 publications with APOLD1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with APOLD1 and Blood
 Muscle Antibodies  >2 publications with APOLD1 and Muscle
 Parathyroid Antibodies  >1 publications with APOLD1 and Parathyroid
 Connective Tissue Antibodies  >1 publications with APOLD1 and Connective Tissue
 Nerve Antibodies  >1 publications with APOLD1 and Nerve
 Lung Antibodies  >1 publications with APOLD1 and Lung
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