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anti-AQP3 antibody :: Rabbit AQP3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS127924
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AQP3, Polyclonal Antibody

 Also Known As   


 Product Gene Name   

anti-AQP3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 607457
 3D Structure    ModBase 3D Structure for Q92482
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Species    Human
 Route    Synthetic Peptide
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 Other Notes    Small volumes of anti-AQP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-AQP3 antibody    Polyclonal
 Applications Tested/Suitable for anti-AQP3 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-AQP3 antibody    Western blot analysis of extracts of various cell lines, using AQP3 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.
anti-AQP3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-AQP3 antibody    Immunohistochemistry of paraffin-embedded rat kidney using AQP3 antibody at dilution of 1:50 (40x lens).
anti-AQP3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for AQP3. It may not necessarily be applicable to this product.
 NCBI GI #    2497938
 NCBI GeneID    360
 NCBI Accession #    Q92482.2 [Other Products]
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 UniProt Primary Accession #    Q92482 [Other Products]
 UniProt Secondary Accession #    O00108; Q6FGT2; Q6FGW6; A8K843; B2RE16; D3DRL3 [Other Products]
 UniProt Related Accession #    Q92482 [Other Products]
 Molecular Weight    292
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 NCBI Official Full Name    Aquaporin-3
 NCBI Official Synonym Full Names    aquaporin 3 (Gill blood group)
 NCBI Official Symbol    AQP3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    aquaporin-3; aquaglyceroporin-3; aquaporin 3 (GIL blood group)
 UniProt Protein Name    Aquaporin-3
 UniProt Synonym Protein Names   
 Protein Family    Aquaporin
 UniProt Gene Name    AQP3 [Similar Products]
 UniProt Synonym Gene Names    AQP-3 [Similar Products]
 UniProt Entry Name    AQP3_HUMAN
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 NCBI Summary for AQP3    This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. [provided by RefSeq, Aug 2011]
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 UniProt Comments for AQP3    AQP3: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism. Belongs to the MIP/aquaporin (TC 1.A.8) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Channel, misc.; Transporter, aquaporin family; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: integral to plasma membrane; basolateral plasma membrane; cytoplasm; plasma membrane; integral to membrane; intercellular junction

Molecular Function: transporter activity; urea transmembrane transporter activity; water channel activity; glycerol channel activity

Biological Process: positive regulation of immune system process; glycerol transport; cellular water homeostasis; response to retinoic acid; water transport; excretion; odontogenesis; response to vitamin D; transport; renal water homeostasis; response to calcium ion; regulation of keratinocyte differentiation; transmembrane transport

Disease: Gil Blood Group
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 Research Articles on AQP3    1. Investigated both AQP3 expression in the skin of an experimental burn model. Observations suggest that dermal AQP3 gene expression was increased to maintain water homeostasis in response to dehydration from burn.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AQP3 antibodyPathways associated with anti-AQP3 antibody
 Reference Product  PubMed Publications
 AQP2 antibody  >222 publications with AQP3 and AQP2
 KLF4 antibody  >2 publications with AQP3 and KLF4
 MET antibody  >1 publications with AQP3 and MET
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway antibodies  Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway antibodies  Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
Diseases associated with anti-AQP3 antibodyOrgans/Tissues associated with anti-AQP3 antibody
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >55 publications with AQP3 and Kidney Diseases
 Disease Models, Animal Antibodies  >45 publications with AQP3 and Disease Models, Animal
 Edema Antibodies  >25 publications with AQP3 and Edema
 Cardiovascular Diseases Antibodies  >23 publications with AQP3 and Cardiovascular Diseases
 Inflammation Antibodies  >17 publications with AQP3 and Inflammation
 Nervous System Diseases Antibodies  >14 publications with AQP3 and Nervous System Diseases
 Lung Diseases Antibodies  >14 publications with AQP3 and Lung Diseases
 Carcinoma, Squamous Cell Antibodies  >14 publications with AQP3 and Carcinoma, Squamous Cell
 Liver Diseases Antibodies  >11 publications with AQP3 and Liver Diseases
 Lung Neoplasms Antibodies  >9 publications with AQP3 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >225 publications with AQP3 and Kidney
 Blood Antibodies  >131 publications with AQP3 and Blood
 Skin Antibodies  >84 publications with AQP3 and Skin
 Lung Antibodies  >58 publications with AQP3 and Lung
 Liver Antibodies  >46 publications with AQP3 and Liver
 Brain Antibodies  >44 publications with AQP3 and Brain
 Intestine Antibodies  >42 publications with AQP3 and Intestine
 Eye Antibodies  >36 publications with AQP3 and Eye
 Heart Antibodies  >28 publications with AQP3 and Heart
 Salivary Gland Antibodies  >27 publications with AQP3 and Salivary Gland
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