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anti-AVP antibody :: Rabbit ARG-VASOPRESSIN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS221211 anti-AVP antibody
Unit / Price
0.05 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARG-VASOPRESSIN (AVP), Polyclonal Antibody

★Popular Item★
 Also Known As   

RABBIT ANTI ARG-VASOPRESSIN

 Product Gene Name   

anti-AVP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    125700
 3D Structure    ModBase 3D Structure for P01185
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Broad (Expected from Sequence)
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 Specificity    This item is specific for arginine vasopressin, also known as antidiuretic hormone. Arginine vasopressin, is a nine amino acid peptide secreted from the posterior pituitary in response to reductions in plasma volume and increases is plasma osmolarity. Its release triggers water reabsorption due to theinsertion of aquaporins in the membranes of kidney tubules which transport solute-free water through tubular cells and back into the blood.
 Form/Format    Purified
Purified IgG - liquid
 Concentration    Approximate Protein Concentration: 5.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
Preparation
 Immunogen    Synthetic arginine vasopressin conjugated to bovine thyroglobulin
Histology Positive Control Tissue
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-AVP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-AVP antibody

   MBS221211 is specific for arginine vasopressin, also known as antidiuretic hormone.Arginine vasopressin, is a nine amino acid peptide secreted from the posterior pituitary in response to reductions in plasma volume and increases is plasma osmolarity. Its release triggers water reabsorption due to the insertion of aquaporins in the membranes of kidney tubules which transport solute-free water through tubular cells and back into the blood.
 Applications Tested/Suitable for anti-AVP antibody   

Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin

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NCBI/Uniprot data below describe general gene information for AVP. It may not necessarily be applicable to this product.
 NCBI GI #    13259533
 NCBI GeneID    551
 NCBI Accession #    NP_000481.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000490.4 [Other Products]
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 UniProt Primary Accession #    P01185 [Other Products]
 UniProt Secondary Accession #    O14935; A0AV35 [Other Products]
 UniProt Related Accession #    P01185 [Other Products]
 Molecular Weight    17,325 Da [Similar Products]
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 NCBI Official Full Name    vasopressin-neurophysin 2-copeptin preproprotein
 NCBI Official Synonym Full Names    arginine vasopressin
 NCBI Official Symbol    AVP [Similar Products]
 NCBI Official Synonym Symbols   
VP; ADH; ARVP; AVRP; AVP-NPII
[Similar Products]
 NCBI Protein Information    vasopressin-neurophysin 2-copeptin; antidiuretic hormone; neurohypophyseal; prepro-AVP-NP II; prepro-arginine-vasopressin-neurophysin II; vasopressin-neurophysin II-copeptin
 UniProt Protein Name    Vasopressin-neurophysin 2-copeptin
 UniProt Synonym Protein Names   
AVP-NPIICleaved into the following 3 chains:Arg-vasopressinAlternative name(s):Arginine-vasopressin
 Protein Family    Neurophysin
 UniProt Gene Name    AVP [Similar Products]
 UniProt Synonym Gene Names    ARVP; VP [Similar Products]
 UniProt Entry Name    NEU2_HUMAN
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 NCBI Summary for AVP    This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
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 UniProt Comments for AVP    AVP: Neurophysin 2 specifically binds vasopressin. Defects in AVP are the cause of diabetes insipidus, neurohypophyseal (NDI). A disease characterized by persistent thirst, polydipsia and polyuria. Affected individuals are apparently normal at birth, but characteristically develop symptoms of vasopression deficiency during childhood. Belongs to the vasopressin/oxytocin family.

Protein type: Secreted, signal peptide; Secreted; Hormone

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: extracellular space; dendrite; extracellular region; cytosol; secretory granule

Molecular Function: neuropeptide hormone activity; signal transducer activity; V1A vasopressin receptor binding; caspase inhibitor activity; neurohypophyseal hormone activity; V1B vasopressin receptor binding; receptor binding; protein kinase activity

Biological Process: response to nicotine; circadian rhythm; water transport; positive regulation of glutamate secretion; positive regulation of cellular pH reduction; locomotory behavior; positive regulation of systemic arterial blood pressure; negative regulation of caspase activity; signal transduction; protein amino acid phosphorylation; elevation of cytosolic calcium ion concentration; hyperosmotic salinity response; cell-cell signaling; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; transmembrane transport; positive regulation of prostaglandin biosynthetic process; penile erection; grooming behavior; vasoconstriction; sodium-independent organic anion transport; generation of precursor metabolites and energy; maternal behavior; response to testosterone stimulus; social behavior; positive regulation of peptidyl-serine phosphorylation; positive regulation of cell growth; negative regulation of female receptivity; response to ethanol; negative regulation of transmission of nerve impulse; positive regulation of vasoconstriction; renal water homeostasis; negative regulation of apoptosis

Disease: Diabetes Insipidus, Neurohypophyseal
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 Research Articles on AVP    1. Serum levels of cortisol, copeptin, and their ratio could differentiate severe sickle cell anemia from mild or moderate disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AVP antibodyPathways associated with anti-AVP antibody
 Reference Product  PubMed Publications
 AVPR1B antibody  >2285 publications with AVP and AVPR1B
 JUN antibody  >747 publications with AVP and JUN
 CRH antibody  >538 publications with AVP and CRH
 AQP2 antibody  >223 publications with AVP and AQP2
 AVPR2 antibody  >45 publications with AVP and AVPR2
 OXTR antibody  >13 publications with AVP and OXTR
 NOS3 antibody  >7 publications with AVP and NOS3
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway antibodies  BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with anti-AVP antibodyOrgans/Tissues associated with anti-AVP antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >927 publications with AVP and Cardiovascular Diseases
 Kidney Diseases Antibodies  >635 publications with AVP and Kidney Diseases
 Hypertension Antibodies  >545 publications with AVP and Hypertension
 Diabetes Insipidus Antibodies  >508 publications with AVP and Diabetes Insipidus
 Brain Diseases Antibodies  >475 publications with AVP and Brain Diseases
 Hyponatremia Antibodies  >343 publications with AVP and Hyponatremia
 Dehydration Antibodies  >319 publications with AVP and Dehydration
 Heart Failure Antibodies  >265 publications with AVP and Heart Failure
 Hypotension Antibodies  >264 publications with AVP and Hypotension
 Shock Antibodies  >208 publications with AVP and Shock
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3361 publications with AVP and Brain
 Kidney Antibodies  >1583 publications with AVP and Kidney
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