NP_005426.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
60,056 Da
NCBI Official Full Name
rho guanine nucleotide exchange factor 5
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor (GEF) 5
NCBI Protein Information
rho guanine nucleotide exchange factor 5; p60 TIM; ephexin-3; oncogene TIM; guanine nucleotide regulatory protein TIM; transforming immortalized mammary oncogene
UniProt Protein Name
Rho guanine nucleotide exchange factor 5
UniProt Synonym Protein Names
Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM
UniProt Synonym Gene Names
UniProt Entry Name
ARHG5_HUMAN
NCBI Summary for ARHGEF5
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
UniProt Comments for ARHGEF5
ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein; GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7q35
Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; GTP binding
Biological Process: myeloid dendritic cell chemotaxis; actin cytoskeleton organization and biogenesis
Research Articles on ARHGEF5
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Products associated with anti-ARHGEF5 antibody
Pathways associated with anti-ARHGEF5 antibody
Diseases associated with anti-ARHGEF5 antibody
Organs/Tissues associated with anti-ARHGEF5 antibody
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