NP_005722.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
actin-related protein 2/3 complex subunit 2
NCBI Official Synonym Full Names
actin related protein 2/3 complex, subunit 2, 34kDa
NCBI Official Synonym Symbols
ARC34; PRO2446; p34-Arc; PNAS-139 [Similar Products]
NCBI Protein Information
actin-related protein 2/3 complex subunit 2
UniProt Protein Name
Actin-related protein 2/3 complex subunit 2
UniProt Synonym Protein Names
Arp2/3 complex 34 kDa subunit; p34-ARC
UniProt Synonym Gene Names
UniProt Entry Name
ARPC2_HUMAN
NCBI Summary for ARPC2
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for ARPC2
ARPC2: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Belongs to the ARPC2 family.
Protein type: Actin-binding; Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 2q36.1
Cellular Component: Golgi apparatus; neuron projection; Arp2/3 protein complex; focal adhesion; cytoplasm; leading edge; plasma membrane; synapse; cytosol; endosome; actin cytoskeleton
Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; kinesin binding
Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility
Product References and Citations for anti-ARPC2 antibody
Welch M.D.,et al.J. Cell Biol. 138:375-384(1997). Couch F.J.,et al.Genomics 36:86-99(1996). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003). Zhang C.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Research Articles on ARPC2
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Products associated with anti-ARPC2 antibody
Diseases associated with anti-ARPC2 antibody
Organs/Tissues associated with anti-ARPC2 antibody
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