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| Product Name
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ARR3 / Cone Arrestin, Polyclonal Antibody ★Popular Item★
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| Also Known As
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Rabbit Polyclonal (IgG) to Human ARR3 / Cone Arrestin
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| Product Synonym Names
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Anti-ARR3 / Cone Arrestin Antibody (aa339-388) IHC-plus; ARR3; Arrestin 4; Arrestin-C; ARRX; C-arrestin; CArr; Cone arrestin; Retinal cone arrestin-3; X-arrestin; CAR; Human ARR3; Cone Arrestin
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| OMIM
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301770
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| 3D Structure
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ModBase 3D Structure for P36575
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| Clonality
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Polyclonal
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| Isotype
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IgG
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| Host
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Rabbit
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| Species Reactivity
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Human
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| Specificity
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ARR3 Antibody detects endogenous levels of total ARR3 protein.
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| Purity/Purification
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Immunoaffinity Purified
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| Form/Format
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PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
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| Concentration
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1 mg/ml (lot specific)
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| Target Species
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Human
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| Immunogen Description
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Synthetic peptide from human ARRC (aa339-388).
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| Immunogen
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ARR3 / Cone Arrestin antibody was raised against synthetic peptide from human ARRC (aa339-388).
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| Antigen Modification
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aa339-388
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| Preparation and Storage
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Store at -20 degree C for up to one year.
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| Other Notes
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Small volumes of anti-ARR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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TOP
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| Applications Tested/Suitable for anti-ARR3 antibody
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Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA)
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| Application Notes for anti-ARR3 antibody
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ELISA (1:5000), IHC (20 ug/ml), WB (1:500 - 1:1000)
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| Immunohistochemistry (IHC) of anti-ARR3 antibody
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Anti-ARR3 / Cone Arrestin antibody IHC staining of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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| Western Blot (WB) of anti-ARR3 antibody
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Western blot of extracts from LOVO cells, using ARRC Antibody. The lane on the right is treated with the synthesized peptide.
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TOP
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| NCBI/Uniprot data below describe general gene information for ARR3. It may not necessarily be applicable to this product. |
| NCBI GI #
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156071467
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| NCBI GeneID
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407
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| NCBI Accession #
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NP_004303.2
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_004312.2
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[Other Products]
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| UniProt Primary Accession #
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P36575
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[Other Products]
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| UniProt Secondary Accession #
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Q5JT23; Q5JT24; Q6IBF5; Q96EN2; B5B0B9
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[Other Products]
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| UniProt Related Accession #
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P36575
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[Other Products]
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| Molecular Weight
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39,667 Da
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TOP
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| NCBI Official Full Name
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arrestin-C
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| NCBI Official Synonym Full Names
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arrestin 3, retinal (X-arrestin)
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| NCBI Official Symbol
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ARR3
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[Similar Products]
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| NCBI Official Synonym Symbols
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ARRX
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[Similar Products]
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| NCBI Protein Information
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arrestin-C; cArr; C-arrestin; X-arrestin; arrestin 4; cone arrestin; retinal cone arrestin-3
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| UniProt Protein Name
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Arrestin-C
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| UniProt Synonym Protein Names
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Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
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| Protein Family
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Arrestin
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| UniProt Gene Name
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ARR3
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[Similar Products]
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| UniProt Synonym Gene Names
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ARRX; CAR; C-arrestin; cArr
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[Similar Products]
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| UniProt Entry Name
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ARRC_HUMAN
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| UniProt Comments for ARR3
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ARR3: May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins. Belongs to the arrestin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: Xcen-q21
Cellular Component: photoreceptor inner segment; photoreceptor outer segment; cytoplasm; synapse
Molecular Function: protein binding; opsin binding; phosphoprotein binding
Biological Process: regulation of protein amino acid phosphorylation; visual perception; endocytosis; signal transduction
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TOP
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| Research Articles on ARR3
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1. The 25-amino acid N-domain element of arrestin 3 has the highest affinity for JNK3alpha2, suggesting that it is the key site for JNK3alpha2 docking.
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TOP
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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TOP
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| Products associated with anti-ARR3 antibody | Pathways associated with anti-ARR3 antibody |
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TOP
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Antibody 
