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anti-ARRDC3 antibody :: Rabbit anti-Human ARRDC3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1496906
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARRDC3, Polyclonal Antibody

★Popular Item★
 Also Known As   

ARRDC3 Antibody

 Product Synonym Names    Arrestin domain-containing protein 3; ARRDC3; KIAA1376; TBP-2-like inducible membrane protein1
 Product Gene Name   

anti-ARRDC3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612464
 3D Structure    ModBase 3D Structure for Q96B67
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Arrestin domain-containing protein 3 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-135441 / sc-135442
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ARRDC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ARRDC3 antibody

   Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550).
 Applications Tested/Suitable for anti-ARRDC3 antibody   

ELISA (EIA), Western Blot (WB)

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 Western Blot (WB) of anti-ARRDC3 antibody    Western Blot
Positive WB detected in:MCF-7 whole cell lysate,Mouse skeletal muscle tissue
All lanes: ARRDC3 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa

anti-ARRDC3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ARRDC3. It may not necessarily be applicable to this product.
 NCBI GI #    32698736
 NCBI GeneID    57561
 NCBI Accession #    NP_065852.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020801.2 [Other Products]
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 UniProt Primary Accession #    Q96B67 [Other Products]
 UniProt Secondary Accession #    Q9P2H1; A8K6T8 [Other Products]
 UniProt Related Accession #    Q96B67 [Other Products]
 Molecular Weight    46,395 Da
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 NCBI Official Full Name    arrestin domain-containing protein 3
 NCBI Official Synonym Full Names    arrestin domain containing 3
 NCBI Official Symbol    ARRDC3 [Similar Products]
 NCBI Official Synonym Symbols   
TLIMP
[Similar Products]
 NCBI Protein Information    arrestin domain-containing protein 3
 UniProt Protein Name    Arrestin domain-containing protein 3
 UniProt Synonym Protein Names   
TBP-2-like inducible membrane protein
 Protein Family    Arrestin domain-containing protein
 UniProt Gene Name    ARRDC3 [Similar Products]
 UniProt Synonym Gene Names    KIAA1376; TLIMP [Similar Products]
 UniProt Entry Name    ARRD3_HUMAN
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 UniProt Comments for ARRDC3    ARRDC3: Belongs to the arrestin family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 5q14.3

Cellular Component: early endosome; endosome; lysosome; plasma membrane

Molecular Function: beta-3 adrenergic receptor binding; protein binding

Biological Process: negative regulation of heat generation; negative regulation of multicellular organismal metabolic process; positive regulation of ubiquitin-protein ligase activity; skin development; thermoregulation
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 Research Articles on ARRDC3    1. Promoter hypermethylation is an important mechanism of the transcriptional inactivation of ARRDC3 in invasive ductal breast carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARRDC3 antibodyDiseases associated with anti-ARRDC3 antibody
 Reference Product  PubMed Publications
 NEDD4 antibody  >6 publications with ARRDC3 and NEDD4
 ADRB2 antibody  >3 publications with ARRDC3 and ADRB2
 WWP2 antibody  >1 publications with ARRDC3 and WWP2
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >6 publications with ARRDC3 and Breast Neoplasms
 Brain Diseases Antibodies  >3 publications with ARRDC3 and Brain Diseases
 Heart Defects, Congenital Antibodies  >1 publications with ARRDC3 and Heart Defects, Congenital
 Congenital Abnormalities Antibodies  >1 publications with ARRDC3 and Congenital Abnormalities
 Hypertension Antibodies  >1 publications with ARRDC3 and Hypertension
 Heart Diseases Antibodies  >1 publications with ARRDC3 and Heart Diseases
Organs/Tissues associated with anti-ARRDC3 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >3 publications with ARRDC3 and Eye
 Nerve Antibodies  >2 publications with ARRDC3 and Nerve
 Heart Antibodies  >2 publications with ARRDC3 and Heart
 Skin Antibodies  >2 publications with ARRDC3 and Skin
 Brain Antibodies  >2 publications with ARRDC3 and Brain
 Vascular Antibodies  >1 publications with ARRDC3 and Vascular
 Prostate Antibodies  >1 publications with ARRDC3 and Prostate
 Connective Tissue Antibodies  >1 publications with ARRDC3 and Connective Tissue
 Lymph Node Antibodies  >1 publications with ARRDC3 and Lymph Node
 Uncharacterized Tissue Antibodies  >1 publications with ARRDC3 and Uncharacterized Tissue
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