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anti-ART1 antibody :: Rabbit anti-Human ART1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9130406
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ART1, Polyclonal Antibody

 Also Known As   

ART1 Polyclonal Antibody

 Product Gene Name   

anti-ART1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601625
 3D Structure    ModBase 3D Structure for P52961
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Affinity purification
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 Immunogen    Recombinant protein of human ART1
 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.   
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-ART1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ART1 antibody    Polyclonal
 Applications Tested/Suitable for anti-ART1 antibody   

Western Blot (WB)

 Application Notes for anti-ART1 antibody    WB: 1:500 - 1:2000
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 Western Blot (WB) of anti-ART1 antibody    Western blot analysis of extracts of various cell lines, using ART1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-ART1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ART1. It may not necessarily be applicable to this product.
 NCBI GI #    158634472
 NCBI GeneID    417
 NCBI Accession #    NP_004305.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004314.2 [Other Products]
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 UniProt Primary Accession #    P52961 [Other Products]
 UniProt Secondary Accession #    Q6NTD2; Q96KT9 [Other Products]
 UniProt Related Accession #    P52961 [Other Products]
 Molecular Weight    Calculated MW: 36kDa
Molecular Weight: 327
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 NCBI Official Full Name    GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
 NCBI Official Synonym Full Names    ADP-ribosyltransferase 1
 NCBI Official Symbol    ART1 [Similar Products]
 NCBI Official Synonym Symbols   
RT6; ART2; ARTC1; CD296
[Similar Products]
 NCBI Protein Information    GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
 UniProt Protein Name    GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
 UniProt Synonym Protein Names   
ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1; CD_antigen: CD296
 Protein Family    Arrestin family protein
 UniProt Gene Name    ART1 [Similar Products]
 UniProt Synonym Gene Names    ARTC1 [Similar Products]
 UniProt Entry Name    NAR1_HUMAN
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 NCBI Summary for ART1    ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ART1    ART1: Has ADP-ribosyltransferase activity toward GLP1R. Belongs to the Arg-specific ADP-ribosyltransferase family.

Protein type: Membrane protein, GPI anchor; EC 2.4.2.31; Transferase

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: cell surface; integral to plasma membrane; plasma membrane; sarcoplasmic reticulum membrane

Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity

Biological Process: innate immune response; protein amino acid ADP-ribosylation
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 Research Articles on ART1    1. This study provides evidence that ARTC1 is activated during the endoplasmic-reticulum stress response, which results in acute ADP-ribosylation of GRP78/BiP paralleling translational inhibition.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ART1 antibodyPathways associated with anti-ART1 antibody
 Reference Product  PubMed Publications
 PDGFB antibody  >2 publications with ART1 and PDGFB
 PARP1 antibody  >2 publications with ART1 and PARP1
 Products by Pathway  Pathway Diagram
 Alpha-defensins Pathway antibodies  Alpha-defensins Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
Diseases associated with anti-ART1 antibodyOrgans/Tissues associated with anti-ART1 antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >9 publications with ART1 and Immune System Diseases
 Inflammation Antibodies  >4 publications with ART1 and Inflammation
 Vascular Diseases Antibodies  >3 publications with ART1 and Vascular Diseases
 Fibrosis Antibodies  >3 publications with ART1 and Fibrosis
 Liver Diseases Antibodies  >2 publications with ART1 and Liver Diseases
 Disease Models, Animal Antibodies  >2 publications with ART1 and Disease Models, Animal
 Carcinoma, Hepatocellular Antibodies  >1 publications with ART1 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >1 publications with ART1 and Kidney Diseases
 Neoplasm Metastasis Antibodies  >1 publications with ART1 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >1 publications with ART1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >15 publications with ART1 and Muscle
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