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anti-ASB7 antibody :: Rabbit anti-Human ASB7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7001179
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ASB7, Polyclonal Antibody

★Popular Item★
 Also Known As   

ASB7 Antibody

 Product Synonym Names    Ankyrin repeat and SOCS box protein 7; ASB-7; ASB7
 Product Gene Name   

anti-ASB7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    615052
 3D Structure    ModBase 3D Structure for Q9H672
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%,Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Ankyrin repeat and SOCS box protein 7 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-83110
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ASB7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ASB7 antibody

   Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 Applications Tested/Suitable for anti-ASB7 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-ASB7 antibody    Western blot
All lanes: ASB7 antibody at 8ug/ml+A431 whole cell lysate
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 37,31 kDa
Observed band size: 36 kDa

anti-ASB7 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ASB7 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7001179 at dilution of 1:100
anti-ASB7 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ASB7. It may not necessarily be applicable to this product.
 NCBI GI #    30089994
 NCBI GeneID    140460
 NCBI Accession #    NP_078984.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024708.3 [Other Products]
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 UniProt Primary Accession #    Q9H672 [Other Products]
 UniProt Secondary Accession #    Q6GSJ6; Q7Z4S3; A8K1E5 [Other Products]
 UniProt Related Accession #    Q9H672 [Other Products]
 Molecular Weight    30,713 Da
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 NCBI Official Full Name    ankyrin repeat and SOCS box protein 7 isoform 1
 NCBI Official Synonym Full Names    ankyrin repeat and SOCS box containing 7
 NCBI Official Symbol    ASB7 [Similar Products]
 NCBI Protein Information    ankyrin repeat and SOCS box protein 7
 UniProt Protein Name    Ankyrin repeat and SOCS box protein 7
 Protein Family    Ankyrin repeat and SOCS box protein
 UniProt Gene Name    ASB7 [Similar Products]
 UniProt Synonym Gene Names    ASB-7 [Similar Products]
 UniProt Entry Name    ASB7_HUMAN
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 NCBI Summary for ASB7    The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ASB7    ASB7: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q26.3

Cellular Component: intracellular

Molecular Function: protein binding

Biological Process: protein ubiquitination
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ASB7 antibodyDiseases associated with anti-ASB7 antibody
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with ASB7 and Nervous System Diseases
Organs/Tissues associated with anti-ASB7 antibody
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with ASB7 and Nerve
 Eye Antibodies  >1 publications with ASB7 and Eye
 Prostate Antibodies  >1 publications with ASB7 and Prostate
 Muscle Antibodies  >1 publications with ASB7 and Muscle
 Kidney Antibodies  >1 publications with ASB7 and Kidney
 Testis Antibodies  >1 publications with ASB7 and Testis
 Brain Antibodies  >1 publications with ASB7 and Brain
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