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anti-ASH1 antibody :: Rabbit ASH1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9401209
Testing Data
Unit / Price
0.1 mL  /  $320 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ASH1, Polyclonal Antibody

★Popular Item★
 Also Known As   

ASH1 Antibody

 Product Gene Name   

anti-ASH1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607999
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Not yet tested in other species
 Purity/Purification    Affinity purified
 Form/Format    PBS, pH 7.4 with 0.02% Sodium Azide
 Concentration    1.0 mg/ml (lot specific)
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 Immunogen Type    Peptide-KLH
 Immunogen Description    Synthetic peptide conjugated to KLH
 Target Name    ASH1
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 Preparation and Storage    This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
 Other Notes    Small volumes of anti-ASH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ASH1 antibody    Total protein Ab
 Applications Tested/Suitable for anti-ASH1 antibody   

ELISA (EIA), Western Blot (WB)

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 Testing Data of anti-ASH1 antibody    anti-ASH1 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for ASH1. It may not necessarily be applicable to this product.
 NCBI GI #    7739725
 NCBI GeneID    55870
 NCBI Accession #    AAF68983.1 [Other Products]
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 UniProt Secondary Accession #    Q59GP1; Q5T714; Q5T715; Q9P2C7 [Other Products]
 UniProt Related Accession #    Q9NR48 [Other Products]
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 NCBI Official Full Name    ASH1
 NCBI Official Synonym Full Names    ash1 (absent, small, or homeotic)-like (Drosophila)
 NCBI Official Symbol    ASH1L [Similar Products]
 NCBI Official Synonym Symbols   
ASH1; KMT2H; ASH1L1
[Similar Products]
 NCBI Protein Information    histone-lysine N-methyltransferase ASH1L
 UniProt Protein Name    Histone-lysine N-methyltransferase ASH1L
 UniProt Synonym Protein Names   
ASH1-like protein; huASH1; Absent small and homeotic disks protein 1 homolog; Lysine N-methyltransferase 2H
 Protein Family    Hemolysin
 UniProt Gene Name    ASH1L [Similar Products]
 UniProt Synonym Gene Names    KIAA1420; KMT2H; huASH1 [Similar Products]
 UniProt Entry Name    ASH1L_HUMAN
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 NCBI Summary for ASH1    This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ASH1    ASH1L: a protein methyltransferase that specifically methylates K36 of histone H3 (H3K36me). A member of the trithorax group (trxG) of transcriptional activators that is required for proper expression of Hox genes and is preferentially expressed in haematopoietic stem cells. Widely expressed, with high levels in brain, heart and kidney. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.

Protein type: Cell adhesion; EC 2.1.1.43; Amino Acid Metabolism - lysine degradation; Methyltransferase, protein lysine; Methyltransferase

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: nucleoplasm; Golgi apparatus; tight junction; cytoplasm; chromosome; nucleus

Molecular Function: DNA binding; zinc ion binding; histone lysine N-methyltransferase activity (H3-K4 specific); chromatin binding

Biological Process: transcription from RNA polymerase II promoter; cell-cell signaling; negative regulation of MAPKKK cascade; interleukin-6 production; histone H3-K4 methylation; negative regulation of acute inflammatory response; positive regulation of transcription from RNA polymerase II promoter; negative regulation of I-kappaB kinase/NF-kappaB cascade; DNA packaging
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 Research Articles on ASH1    1. These data demonstrate that miR-142-3p downregulation has a role in thyroid tumorigenesis, by regulating ASH1L and MLL1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ASH1 antibodyDiseases associated with anti-ASH1 antibody
 Products by Pathway  Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >7 publications with ASH1 and Adenocarcinoma
 Lung Neoplasms Antibodies  >5 publications with ASH1 and Lung Neoplasms
 Brain Diseases Antibodies  >3 publications with ASH1 and Brain Diseases
 Liver Neoplasms Antibodies  >2 publications with ASH1 and Liver Neoplasms
 Death Antibodies  >2 publications with ASH1 and Death
 Liver Diseases Antibodies  >2 publications with ASH1 and Liver Diseases
 Memory Disorders Antibodies  >1 publications with ASH1 and Memory Disorders
 Abnormalities, Drug-Induced Antibodies  >1 publications with ASH1 and Abnormalities, Drug-Induced
 Inflammation Antibodies  >1 publications with ASH1 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >1 publications with ASH1 and Cell Transformation, Neoplastic
Organs/Tissues associated with anti-ASH1 antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with ASH1 and Lung
 Bone Antibodies  >3 publications with ASH1 and Bone
 Liver Antibodies  >3 publications with ASH1 and Liver
 Eye Antibodies  >2 publications with ASH1 and Eye
 Embryonic Tissue Antibodies  >2 publications with ASH1 and Embryonic Tissue
 Blood Antibodies  >2 publications with ASH1 and Blood
 Brain Antibodies  >2 publications with ASH1 and Brain
 Muscle Antibodies  >1 publications with ASH1 and Muscle
 Thyroid Antibodies  >1 publications with ASH1 and Thyroid
 Adrenal Gland Antibodies  >1 publications with ASH1 and Adrenal Gland
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