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anti-AHSG antibody :: Sheep ASIALOFETUIN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS220674 anti-AHSG antibody
Unit / Price
1 mL  /  $375 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ASIALOFETUIN (AHSG), Polyclonal Antibody

★Popular Item★
 Also Known As   

SHEEP ANTI BOVINE ASIALOFETUIN

 Product Gene Name   

anti-AHSG antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P12763
 Clonality    Polyclonal
 Isotype    IgG
 Host    Sheep
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 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 5.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
Preparation
 Buffer Solution    Phosphate buffered saline
 Target Species    Bovine
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-AHSG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-AHSG antibody

   Sheep anti Bovine asialofetuin antibody recognizes bovine Alpha-2-HS-glycoprotein, also known as asialofetuin or fetuin-A. Asialofetuin is a 359 amino acid ~55kDa secreted glycoprotein containing two cystatin fetuin-A-type domains. Asialofetuin is produced in the liver and bone marrow and acts as a negative acute-phase protein attenuating the inflammatory response to acute injury (Wang et al. 2010). In a simple antigen down ELISA assay Sheep anti Bovine asialofetuin antibody reacts with: asialofetuin (ab at 1/8000) 100%fetuin (ab at 1/2000) 100%fetuin (ab at 1/8000) 50%
 Applications Tested/Suitable for anti-AHSG antibody   

ELISA (EIA)

 Application Notes for anti-AHSG antibody    ELISA: Minimum Dilution: 1/1000; Maximum Dilution: 1/4000
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NCBI/Uniprot data below describe general gene information for AHSG. It may not necessarily be applicable to this product.
 NCBI GI #    27806751
 NCBI GeneID    280988
 NCBI Accession #    NP_776409.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_173984.3 [Other Products]
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 UniProt Primary Accession #    P12763 [Other Products]
 UniProt Secondary Accession #    A6QLF7 [Other Products]
 UniProt Related Accession #    P12763 [Other Products]
 Molecular Weight    38,419 Da [Similar Products]
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 NCBI Official Full Name    alpha-2-HS-glycoprotein
 NCBI Official Synonym Full Names    alpha-2-HS-glycoprotein
 NCBI Official Symbol    AHSG [Similar Products]
 NCBI Protein Information    alpha-2-HS-glycoprotein; asialofetuin; fetuin-A
 UniProt Protein Name    Alpha-2-HS-glycoprotein
 UniProt Synonym Protein Names   
Asialofetuin; Fetuin-A
 Protein Family    Alpha-2-HS-glycoprotein
 UniProt Gene Name    AHSG [Similar Products]
 UniProt Synonym Gene Names    FETUA [Similar Products]
 UniProt Entry Name    FETUA_BOVIN
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 UniProt Comments for AHSG    FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: plasma membrane; vesicle

Molecular Function: protein binding; cysteine protease inhibitor activity

Biological Process: negative regulation of bone mineralization; ossification; positive regulation of phagocytosis; regulation of inflammatory response; acute-phase response
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 Research Articles on AHSG    1. These experiments revealed a second mechanism of long-term mineral ion stabilization by the fetuin-A that is complementary to the formation of calciprotein particles.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-AHSG antibodyOrgans/Tissues associated with anti-AHSG antibody
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >112 publications with AHSG and Kidney Diseases
 Calcinosis Antibodies  >98 publications with AHSG and Calcinosis
 Inflammation Antibodies  >84 publications with AHSG and Inflammation
 Heart Diseases Antibodies  >55 publications with AHSG and Heart Diseases
 Liver Diseases Antibodies  >45 publications with AHSG and Liver Diseases
 Brain Diseases Antibodies  >21 publications with AHSG and Brain Diseases
 Liver Neoplasms Antibodies  >18 publications with AHSG and Liver Neoplasms
 Fatty Liver Antibodies  >16 publications with AHSG and Fatty Liver
 Heart Failure Antibodies  >14 publications with AHSG and Heart Failure
 Carcinoma, Hepatocellular Antibodies  >13 publications with AHSG and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >118 publications with AHSG and Kidney
 Liver Antibodies  >93 publications with AHSG and Liver
 Muscle Antibodies  >34 publications with AHSG and Muscle
 Brain Antibodies  >19 publications with AHSG and Brain
 Ovary Antibodies  >5 publications with AHSG and Ovary
 Uterus Antibodies  >4 publications with AHSG and Uterus
 Whole Body Antibodies  >4 publications with AHSG and Whole Body
 Embryonic Tissue Antibodies  >4 publications with AHSG and Embryonic Tissue
 Testis Antibodies  >2 publications with AHSG and Testis
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