P46597.1
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 33kDa/38kDa/41kDa Observed MW: 52kDa
NCBI Official Full Name
Acetylserotonin O-methyltransferase
NCBI Official Synonym Full Names
acetylserotonin O-methyltransferase
NCBI Protein Information
acetylserotonin O-methyltransferase
UniProt Protein Name
Acetylserotonin O-methyltransferase
UniProt Synonym Protein Names
Hydroxyindole O-methyltransferase; HIOMT
UniProt Synonym Gene Names
NCBI Summary for ASMT
This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for ASMT
ASMT: Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin. Belongs to the methyltransferase superfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tryptophan; EC 2.1.1.4; Methyltransferase
Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.2
Cellular Component: cytosol
Molecular Function: acetylserotonin O-methyltransferase activity; identical protein binding; O-methyltransferase activity; protein homodimerization activity; S-methyltransferase activity
Biological Process: indolalkylamine biosynthetic process; melatonin biosynthetic process; translation
Research Articles on ASMT
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-ASMT antibody
Pathways associated with anti-ASMT antibody
Diseases associated with anti-ASMT antibody
Organs/Tissues associated with anti-ASMT antibody
|