NP_001243142.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
sodium/potassium-transporting ATPase subunit alpha-3 isoform 2
NCBI Official Synonym Full Names
ATPase Na+/K+ transporting subunit alpha 3
NCBI Official Synonym Symbols
RDP; AHC2; CAPOS; DYT12; ATP1A1 [Similar Products]
NCBI Protein Information
sodium/potassium-transporting ATPase subunit alpha-3
UniProt Protein Name
Sodium/potassium-transporting ATPase subunit alpha-3
UniProt Synonym Protein Names
Na(+)/K(+) ATPase alpha(III) subunit; Sodium pump subunit alpha-3
UniProt Synonym Gene Names
NCBI Summary for AT1A3
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for AT1A3
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Research Articles on AT1A3
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Pathways associated with anti-AT1A3 antibody
Diseases associated with anti-AT1A3 antibody
Organs/Tissues associated with anti-AT1A3 antibody
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